Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2590156..2590746 Replicon chromosome
Accession NC_013956
Organism Pantoea ananatis LMG 20103

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PANA_RS11815 Protein ID WP_041457686.1
Coordinates 2590156..2590488 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PANA_RS11820 Protein ID WP_041457688.1
Coordinates 2590489..2590746 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PANA_RS11795 2586715..2586969 - 255 WP_013026202.1 Arc family DNA-binding protein -
PANA_RS11800 2587043..2587747 - 705 WP_013026203.1 phosphohydrolase -
PANA_RS11805 2588360..2589037 + 678 WP_013026204.1 hypothetical protein -
PANA_RS11810 2589143..2589976 + 834 WP_013026205.1 DgsA anti-repressor MtfA -
PANA_RS11815 2590156..2590488 - 333 WP_041457686.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PANA_RS11820 2590489..2590746 - 258 WP_041457688.1 antitoxin Antitoxin
PANA_RS21825 2591094..2591299 - 206 Protein_2318 helix-turn-helix domain-containing protein -
PANA_RS11830 2591801..2592763 - 963 WP_014605551.1 ferrochelatase -
PANA_RS11840 2593512..2594750 + 1239 WP_041457689.1 MFS transporter -
PANA_RS21835 2595038..2595463 - 426 WP_014605549.1 pentapeptide repeat-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-108)

Antitoxin

Antitoxin PemI-like

(4-83)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11945.66 Da        Isoelectric Point: 6.9807

>T24650 WP_041457686.1 NC_013956:c2590488-2590156 [Pantoea ananatis LMG 20103]
MERGEIWLVSLDPNAGHEQSGRRPVLIVSPASFNQFTRLPVVVPVTNGGNFARAAGFTVSLDGAGTKTTGVIRCDQPRTL
DMEARNGKYLERIPEVIVNEVVARLEAILS

Download         Length: 333 bp

>T24650 NC_013956:c2590488-2590156 [Pantoea ananatis LMG 20103]
ATGGAAAGAGGGGAAATCTGGCTCGTTTCACTAGATCCGAATGCCGGGCATGAACAAAGCGGAAGGCGTCCAGTACTGAT
TGTTTCTCCGGCGTCCTTTAATCAGTTTACGCGGCTACCTGTGGTTGTTCCCGTGACCAACGGCGGAAACTTTGCCCGCG
CAGCGGGGTTTACTGTTTCACTGGATGGCGCAGGAACGAAAACAACGGGGGTAATTCGTTGTGACCAGCCCAGAACCCTT
GATATGGAAGCCCGGAACGGCAAATATCTTGAACGAATACCTGAAGTTATTGTGAATGAAGTGGTGGCCAGACTGGAGGC
CATTCTGAGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9281.74 Da        Isoelectric Point: 4.5821

>AT24650 WP_041457688.1 NC_013956:c2590746-2590489 [Pantoea ananatis LMG 20103]
MYTTRLKKVGGSVMLAVPPAVLKTLGLSTDSEVGMTIDSGCLIIEPQKRPRYSLEELLAQCDPHAEISEEGREWIDAPAV
GRELL

Download         Length: 258 bp

>AT24650 NC_013956:c2590746-2590489 [Pantoea ananatis LMG 20103]
ATGTATACCACTCGTCTGAAAAAGGTTGGCGGATCTGTCATGCTGGCGGTCCCTCCCGCCGTGCTGAAAACGCTGGGGCT
GTCGACGGACAGCGAAGTGGGCATGACCATTGATAGTGGCTGCCTCATAATTGAACCTCAAAAACGTCCCCGCTATTCAC
TCGAAGAACTACTGGCGCAGTGCGATCCGCACGCTGAAATTAGCGAAGAGGGTCGGGAATGGATTGATGCGCCTGCGGTG
GGCAGGGAGCTCCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References