Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2570111..2570382 Replicon chromosome
Accession NZ_CP097884
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2570241..2570344 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2570111..2570382 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAG72_RS12235 2566666..2567328 - 663 WP_000944256.1 exodeoxyribonuclease X -
NAG72_RS12240 2567352..2568008 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NAG72_RS12245 2568110..2568340 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NAG72_RS12250 2568479..2568853 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NAG72_RS12255 2568857..2569729 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
NAG72_RS12260 2569742..2570083 + 342 WP_000976476.1 YebY family protein -
- 2570111..2570382 - 272 - - Antitoxin
- 2570241..2570344 + 104 - - Toxin
NAG72_RS12265 2570479..2571135 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NAG72_RS12270 2571136..2571327 - 192 WP_000457842.1 YebW family protein -
NAG72_RS12275 2571432..2571668 - 237 WP_001295499.1 YebV family protein -
NAG72_RS12280 2571786..2573225 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246496 NZ_CP097884:2570241-2570344 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246496 NZ_CP097884:c2570382-2570111 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References