Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1944661..1944932 Replicon chromosome
Accession NZ_CP097883
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1944791..1944894 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1944661..1944932 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAG71_RS09295 1941216..1941878 - 663 WP_000944256.1 exodeoxyribonuclease X -
NAG71_RS09300 1941902..1942558 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NAG71_RS09305 1942660..1942890 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NAG71_RS09310 1943029..1943403 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NAG71_RS09315 1943407..1944279 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
NAG71_RS09320 1944292..1944633 + 342 WP_000976476.1 YebY family protein -
- 1944661..1944932 - 272 - - Antitoxin
- 1944791..1944894 + 104 - - Toxin
NAG71_RS09325 1945029..1945685 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NAG71_RS09330 1945686..1945877 - 192 WP_000457842.1 YebW family protein -
NAG71_RS09335 1945982..1946218 - 237 WP_001295499.1 YebV family protein -
NAG71_RS09340 1946336..1947775 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246469 NZ_CP097883:1944791-1944894 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246469 NZ_CP097883:c1944932-1944661 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References