Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 4023641..4024455 | Replicon | chromosome |
Accession | NZ_CP097882 | ||
Organism | Escherichia coli str. K-12 substr. MG1655 strain K-12 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | NAG70_RS19690 | Protein ID | WP_001054376.1 |
Coordinates | 4023641..4023898 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | U9Z4B8 |
Locus tag | NAG70_RS19695 | Protein ID | WP_001309181.1 |
Coordinates | 4023910..4024455 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NAG70_RS19665 (4018929) | 4018929..4020035 | + | 1107 | WP_001309184.1 | N-acetylneuraminate epimerase | - |
NAG70_RS19670 (4020100) | 4020100..4021080 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
NAG70_RS19675 (4021190) | 4021190..4021395 | + | 206 | Protein_3842 | HNH endonuclease | - |
NAG70_RS19680 (4021663) | 4021663..4022903 | - | 1241 | Protein_3843 | helicase YjhR | - |
NAG70_RS19685 (4023019) | 4023019..4023150 | + | 132 | WP_001309182.1 | hypothetical protein | - |
NAG70_RS19690 (4023641) | 4023641..4023898 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
NAG70_RS19695 (4023910) | 4023910..4024455 | + | 546 | WP_001309181.1 | N-acetyltransferase | Antitoxin |
NAG70_RS19700 (4024511) | 4024511..4025257 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
NAG70_RS19705 (4025426) | 4025426..4025644 | + | 219 | Protein_3848 | hypothetical protein | - |
NAG70_RS19710 (4025682) | 4025682..4025798 | + | 117 | Protein_3849 | VOC family protein | - |
NAG70_RS19715 (4026043) | 4026043..4027164 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
NAG70_RS19720 (4027161) | 4027161..4027439 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
NAG70_RS19725 (4027451) | 4027451..4028764 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimB | 4016135..4032679 | 16544 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T246456 WP_001054376.1 NZ_CP097882:4023641-4023898 [Escherichia coli str. K-12 substr. MG1655]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 182 a.a. Molecular weight: 19956.90 Da Isoelectric Point: 6.3277
>AT246456 WP_001309181.1 NZ_CP097882:4023910-4024455 [Escherichia coli str. K-12 substr. MG1655]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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