Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1959614..1959885 Replicon chromosome
Accession NZ_CP097881
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1959744..1959847 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1959614..1959885 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAG69_RS09385 1956169..1956831 - 663 WP_000944256.1 exodeoxyribonuclease X -
NAG69_RS09390 1956855..1957511 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NAG69_RS09395 1957613..1957843 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NAG69_RS09400 1957982..1958356 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NAG69_RS09405 1958360..1959232 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
NAG69_RS09410 1959245..1959586 + 342 WP_000976476.1 YebY family protein -
- 1959614..1959885 - 272 - - Antitoxin
- 1959744..1959847 + 104 - - Toxin
NAG69_RS09415 1959982..1960638 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NAG69_RS09420 1960639..1960830 - 192 WP_000457842.1 YebW family protein -
NAG69_RS09425 1960935..1961171 - 237 WP_001295499.1 YebV family protein -
NAG69_RS09430 1961289..1962728 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246417 NZ_CP097881:1959744-1959847 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246417 NZ_CP097881:c1959885-1959614 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References