Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3614058..3614701 Replicon chromosome
Accession NZ_CP097870
Organism Thauera sp. GDN1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CKCBHOJB_RS16630 Protein ID WP_270068596.1
Coordinates 3614288..3614701 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CKCBHOJB_RS16625 Protein ID WP_281049779.1
Coordinates 3614058..3614291 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKCBHOJB_RS16605 (CKCBHOJB_03319) 3609243..3610475 + 1233 WP_281049775.1 acetamidase/formamidase family protein -
CKCBHOJB_RS16610 (CKCBHOJB_03320) 3610556..3610900 + 345 WP_281049776.1 zinc ribbon domain-containing protein -
CKCBHOJB_RS16615 (CKCBHOJB_03321) 3611323..3612933 - 1611 WP_281049777.1 hypothetical protein -
CKCBHOJB_RS16620 (CKCBHOJB_03322) 3612936..3613595 - 660 WP_281049778.1 hypothetical protein -
CKCBHOJB_RS16625 (CKCBHOJB_03323) 3614058..3614291 + 234 WP_281049779.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CKCBHOJB_RS16630 (CKCBHOJB_03324) 3614288..3614701 + 414 WP_270068596.1 type II toxin-antitoxin system VapC family toxin Toxin
CKCBHOJB_RS16635 (CKCBHOJB_03325) 3614831..3615868 + 1038 WP_281049780.1 aliphatic amidase -
CKCBHOJB_RS16640 (CKCBHOJB_03326) 3615925..3616896 + 972 WP_281049781.1 D-glycerate dehydrogenase -
CKCBHOJB_RS16645 (CKCBHOJB_03327) 3616897..3617919 - 1023 WP_281049782.1 UDP-N-acetylmuramate dehydrogenase -
CKCBHOJB_RS16650 (CKCBHOJB_03328) 3617921..3618412 - 492 WP_281049783.1 PACE efflux transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - gmd / fcl 3483069..3707240 224171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-57)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15106.32 Da        Isoelectric Point: 5.1663

>T246400 WP_270068596.1 NZ_CP097870:3614288-3614701 [Thauera sp. GDN1]
MSYLIDTNVLSELRRKSPDPGVVAWFSQRPPTTLHLSVLTLGEIRKGIEGVGDEVRKQTLIDWLETDLPTFFTGRILDVN
GAVADRWGRLVAAAGRPLPTIDSLLAATALEHDLVLVTRNTKDFAGLPVEVFNPWTS

Download         Length: 414 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8823.03 Da        Isoelectric Point: 5.8152

>AT246400 WP_281049779.1 NZ_CP097870:3614058-3614291 [Thauera sp. GDN1]
MQEAKARMSELVKRAQTQPQDITLHGKSVAVVISRETFDRLSQAQDSLVDFMRRSPLFGTDDIALEREQSLTREVLF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References