Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 763899..764578 Replicon chromosome
Accession NZ_CP097870
Organism Thauera sp. GDN1

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag CKCBHOJB_RS03430 Protein ID WP_281050636.1
Coordinates 763899..764318 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag CKCBHOJB_RS03435 Protein ID WP_281050637.1
Coordinates 764315..764578 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKCBHOJB_RS03405 (CKCBHOJB_00681) 760099..760632 + 534 WP_281050631.1 DUF3833 domain-containing protein -
CKCBHOJB_RS03410 (CKCBHOJB_00682) 760629..761648 + 1020 WP_281050632.1 SDR family NAD(P)-dependent oxidoreductase -
CKCBHOJB_RS03415 (CKCBHOJB_00683) 761658..762164 + 507 WP_281050633.1 nuclear transport factor 2 family protein -
CKCBHOJB_RS03420 (CKCBHOJB_00684) 762276..762896 + 621 WP_281050634.1 SCO family protein -
CKCBHOJB_RS03425 (CKCBHOJB_00685) 762962..763813 - 852 WP_281050635.1 RNA polymerase sigma factor RpoH -
CKCBHOJB_RS03430 (CKCBHOJB_00686) 763899..764318 - 420 WP_281050636.1 type II toxin-antitoxin system VapC family toxin Toxin
CKCBHOJB_RS03435 (CKCBHOJB_00687) 764315..764578 - 264 WP_281050637.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CKCBHOJB_RS03440 764717..764890 - 174 WP_281050638.1 hypothetical protein -
CKCBHOJB_RS03445 (CKCBHOJB_00688) 764899..765189 - 291 WP_281050639.1 type II toxin-antitoxin system RelE/ParE family toxin -
CKCBHOJB_RS03450 (CKCBHOJB_00689) 765186..765494 - 309 WP_281050640.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
CKCBHOJB_RS03455 (CKCBHOJB_00690) 765627..765998 + 372 WP_281050641.1 type II toxin-antitoxin system VapC family toxin -
CKCBHOJB_RS03460 (CKCBHOJB_00691) 766171..767241 + 1071 WP_281050642.1 porin -
CKCBHOJB_RS03465 (CKCBHOJB_00693) 768053..769165 + 1113 WP_281050643.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

SpoVT-AbrB domain

(11-38)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15600.95 Da        Isoelectric Point: 6.6990

>T246396 WP_281050636.1 NZ_CP097870:c764318-763899 [Thauera sp. GDN1]
VIYLLDTNILIYLIKSQPPGIAQRIDALPESDTLCMSFVTWAELLKGAERSTRKTEVLRRLNALARQVPVRYPADPAICR
HYAEQATRLKEAGTPIGANDLWIACHALAEDATLVTHNTREFRRIAGLCVEDWVSAEKD

Download         Length: 420 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9668.93 Da        Isoelectric Point: 4.5994

>AT246396 WP_281050637.1 NZ_CP097870:c764578-764315 [Thauera sp. GDN1]
METLPSRVFNNGNSQAVRIPAEFRLDTDRVSITRNDAGDLVIHPLRVQRGTALMQALKALREVDDAFVAALESEQEAPLP
VQEREAL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References