Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 78884..79437 Replicon chromosome
Accession NZ_CP097870
Organism Thauera sp. GDN1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKCBHOJB_RS00370 Protein ID WP_281051727.1
Coordinates 79183..79437 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKCBHOJB_RS00365 Protein ID WP_281050104.1
Coordinates 78884..79156 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKCBHOJB_RS00345 (CKCBHOJB_00068) 74795..75352 + 558 WP_281050100.1 elongation factor P -
CKCBHOJB_RS00350 (CKCBHOJB_00069) 75500..76006 + 507 WP_281050101.1 hypothetical protein -
CKCBHOJB_RS00355 (CKCBHOJB_00070) 76137..77300 + 1164 WP_281050102.1 glutaredoxin family protein -
CKCBHOJB_RS00360 (CKCBHOJB_00071) 77288..78682 + 1395 WP_281050103.1 MATE family efflux transporter -
CKCBHOJB_RS00365 (CKCBHOJB_00072) 78884..79156 + 273 WP_281050104.1 CopG family ribbon-helix-helix protein Antitoxin
CKCBHOJB_RS00370 79183..79437 + 255 WP_281051727.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKCBHOJB_RS00375 (CKCBHOJB_00073) 79600..80223 + 624 WP_281050105.1 glutathione S-transferase family protein -
CKCBHOJB_RS00380 (CKCBHOJB_00074) 80708..82423 - 1716 WP_281050106.1 retron Ec67 family RNA-directed DNA polymerase/endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9452.84 Da        Isoelectric Point: 8.0275

>T246395 WP_281051727.1 NZ_CP097870:79183-79437 [Thauera sp. GDN1]
MERCRRFLGVRAPEAARRAGQAIARQLLLLETAPDIGRPFPEAPELRELVIAFGDSGYVALYRHEPADNAVYVLAFRHQK
EAGY

Download         Length: 255 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10453.69 Da        Isoelectric Point: 6.0821

>AT246395 WP_281050104.1 NZ_CP097870:78884-79156 [Thauera sp. GDN1]
MATSLKIDDALKSRVQHLAAQRRRSAHWIMLEAIQQYVEREEARESFTQEALASWAAYKETGRHLTGEEVRTWLNIWGTD
EESAVPECHK

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References