246392

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 3027448..3028211 Replicon chromosome
Accession NZ_CP097858
Organism Vibrio owensii strain GL-605

Toxin (Protein)


Gene name ataT Uniprot ID A0A919BFZ0
Locus tag M8C01_RS13915 Protein ID WP_023584043.1
Coordinates 3027705..3028211 (+) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag M8C01_RS13910 Protein ID WP_000212004.1
Coordinates 3027448..3027714 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8C01_RS13900 3022797..3023906 - 1110 WP_122067050.1 hypothetical protein -
M8C01_RS13905 3023903..3026632 - 2730 WP_122067049.1 DEAD/DEAH box helicase -
M8C01_RS13910 3027448..3027714 + 267 WP_000212004.1 DUF1778 domain-containing protein Antitoxin
M8C01_RS13915 3027705..3028211 + 507 WP_023584043.1 GNAT family N-acetyltransferase Toxin
M8C01_RS13920 3028252..3028638 - 387 WP_023584042.1 TraA family conjugative transfer protein -
M8C01_RS13925 3028635..3029207 - 573 WP_001944091.1 type IV conjugative transfer system lipoprotein TraV -
M8C01_RS13930 3029282..3030571 - 1290 WP_086597841.1 TraB/VirB10 family protein -
M8C01_RS13935 3030574..3031470 - 897 WP_086597854.1 type-F conjugative transfer system secretin TraK -
M8C01_RS13940 3031454..3032080 - 627 WP_000667170.1 TraE/TraK family type IV conjugative transfer system protein -
M8C01_RS13945 3032077..3032358 - 282 WP_000433889.1 type IV conjugative transfer system protein TraL -
M8C01_RS13950 3032539..3032862 + 324 WP_054103799.1 type II toxin-antitoxin system RelE/ParE family toxin -
M8C01_RS13955 3032859..3033137 + 279 WP_054103798.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element sul2 / aph(3'')-Ib / aph(6)-Id / tet(59) - 3002833..3073041 70208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18278.00 Da        Isoelectric Point: 7.2132

>T246392 WP_023584043.1 NZ_CP097858:3027705-3028211 [Vibrio owensii]
MGISAPTLLTDEHQLNAFQCGIEELDTWLRKQALKSQKRGTARVYVVNDTDAHQVVGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDGSAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Download         Length: 507 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9956.48 Da        Isoelectric Point: 5.8580

>AT246392 WP_000212004.1 NZ_CP097858:3027448-3027714 [Vibrio owensii]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References