246389

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3861882..3863140 Replicon chromosome
Accession NZ_CP097857
Organism Pseudomonas sp. B111

Toxin (Protein)


Gene name - Uniprot ID V6AJ34
Locus tag M6E97_RS17920 Protein ID WP_003086331.1
Coordinates 3861882..3862637 (-) Length 252 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID V6AJU7
Locus tag M6E97_RS17925 Protein ID WP_003086329.1
Coordinates 3862772..3863140 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M6E97_RS17910 (M6E97_17880) 3857053..3859596 + 2544 WP_034005179.1 acyl-homoserine-lactone acylase QuiP -
M6E97_RS17915 (M6E97_17885) 3859751..3861112 - 1362 WP_003081943.1 DNA recombination protein RmuC -
M6E97_RS17920 (M6E97_17890) 3861882..3862637 - 756 WP_003086331.1 RES family NAD+ phosphorylase Toxin
M6E97_RS17925 (M6E97_17895) 3862772..3863140 - 369 WP_003086329.1 DUF2384 domain-containing protein Antitoxin
M6E97_RS17930 (M6E97_17900) 3863213..3864499 - 1287 WP_033939236.1 FAD-binding oxidoreductase -
M6E97_RS17935 (M6E97_17905) 3864555..3866144 - 1590 WP_003123191.1 aldehyde dehydrogenase family protein -
M6E97_RS17940 (M6E97_17910) 3866223..3866699 + 477 WP_003140638.1 hypothetical protein -
M6E97_RS17945 (M6E97_17915) 3866702..3866977 - 276 WP_023098713.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(63-207)

Antitoxin

Cro/C1-type helix-turn-helix domain

(23-47)


Sequences

Toxin        


Download         Length: 252 a.a.        Molecular weight: 28236.34 Da        Isoelectric Point: 7.7294

>T246389 WP_003086331.1 NZ_CP097857:c3862637-3861882 [Pseudomonas sp. B111]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA

Download         Length: 756 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13367.63 Da        Isoelectric Point: 9.9874

>AT246389 WP_003086329.1 NZ_CP097857:c3863140-3862772 [Pseudomonas sp. B111]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB V6AJ34

Antitoxin

Source ID Structure
AlphaFold DB V6AJU7

References