Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3861882..3863140 Replicon chromosome
Accession NZ_CP097857
Organism Pseudomonas sp. B111

Toxin (Protein)


Gene name - Uniprot ID V6AJ34
Locus tag M6E97_RS17920 Protein ID WP_003086331.1
Coordinates 3861882..3862637 (-) Length 252 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID V6AJU7
Locus tag M6E97_RS17925 Protein ID WP_003086329.1
Coordinates 3862772..3863140 (-) Length 123 a.a.

Genomic Context

M6E97_RS17910M6E97_RS17940M6E97_RS17915M6E97_RS17920M6E97_RS17925M6E97_RS17930M6E97_RS17935M6E97_RS17945
Location: 3857053..3859596 (2544 bp)
Type: Others
Protein ID: WP_034005179.1
Location: 3866223..3866699 (477 bp)
Type: Others
Protein ID: WP_003140638.1
Location: 3859751..3861112 (1362 bp)
Type: Others
Protein ID: WP_003081943.1
Location: 3861882..3862637 (756 bp)
Type: Toxin
Protein ID: WP_003086331.1
Location: 3862772..3863140 (369 bp)
Type: Antitoxin
Protein ID: WP_003086329.1
Location: 3863213..3864499 (1287 bp)
Type: Others
Protein ID: WP_033939236.1
Location: 3864555..3866144 (1590 bp)
Type: Others
Protein ID: WP_003123191.1
Location: 3866702..3866977 (276 bp)
Type: Others
Protein ID: WP_023098713.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M6E97_RS17910 (M6E97_17880)3857053..3859596+2544WP_034005179.1acyl-homoserine-lactone acylase QuiP-
M6E97_RS17915 (M6E97_17885)3859751..3861112-1362WP_003081943.1DNA recombination protein RmuC-
M6E97_RS17920 (M6E97_17890)3861882..3862637-756WP_003086331.1RES family NAD+ phosphorylaseToxin
M6E97_RS17925 (M6E97_17895)3862772..3863140-369WP_003086329.1DUF2384 domain-containing proteinAntitoxin
M6E97_RS17930 (M6E97_17900)3863213..3864499-1287WP_033939236.1FAD-binding oxidoreductase-
M6E97_RS17935 (M6E97_17905)3864555..3866144-1590WP_003123191.1aldehyde dehydrogenase family protein-
M6E97_RS17940 (M6E97_17910)3866223..3866699+477WP_003140638.1hypothetical protein-
M6E97_RS17945 (M6E97_17915)3866702..3866977-276WP_023098713.1zinc ribbon domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(63-207)

Antitoxin

Cro/C1-type helix-turn-helix domain

(23-47)


Sequences

Toxin        


Download         Length: 252 a.a.        Molecular weight: 28236.34 Da        Isoelectric Point: 7.7294

>T246389 WP_003086331.1 NZ_CP097857:c3862637-3861882 [Pseudomonas sp. B111]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA

Download         Length: 756 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13367.63 Da        Isoelectric Point: 9.9874

>AT246389 WP_003086329.1 NZ_CP097857:c3863140-3862772 [Pseudomonas sp. B111]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBV6AJ34

Antitoxin

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Source
ID
Structure
AlphaFold DBV6AJU7

References