Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2917724..2918945 Replicon chromosome
Accession NZ_CP097857
Organism Pseudomonas sp. B111

Toxin (Protein)


Gene name vapC Uniprot ID A0A0H2Z8V4
Locus tag M6E97_RS13475 Protein ID WP_003110488.1
Coordinates 2918367..2918945 (+) Length 193 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M6E97_RS13470 Protein ID WP_003117666.1
Coordinates 2917724..2918278 (+) Length 185 a.a.

Genomic Context

M6E97_RS13445M6E97_RS13460M6E97_RS13465M6E97_RS13470M6E97_RS13475M6E97_RS13450M6E97_RS13455M6E97_RS13480M6E97_RS13485M6E97_RS13490
Location: 2913296..2913847 (552 bp)
Type: Others
Protein ID: WP_003132721.1
Location: 2914909..2915370 (462 bp)
Type: Others
Protein ID: WP_003102736.1
Location: 2915375..2917570 (2196 bp)
Type: Others
Protein ID: WP_023875495.1
Location: 2917724..2918278 (555 bp)
Type: Antitoxin
Protein ID: WP_003117666.1
Location: 2918367..2918945 (579 bp)
Type: Toxin
Protein ID: WP_003110488.1
Location: 2913844..2914242 (399 bp)
Type: Others
Protein ID: WP_033990114.1
Location: 2914255..2914578 (324 bp)
Type: Others
Protein ID: WP_003102734.1
Location: 2919055..2920242 (1188 bp)
Type: Others
Protein ID: WP_003139884.1
Location: 2920232..2922403 (2172 bp)
Type: Others
Protein ID: WP_003088105.1
Location: 2922393..2923670 (1278 bp)
Type: Others
Protein ID: WP_003088104.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M6E97_RS13445 (M6E97_13425)2913296..2913847+552WP_003132721.1XRE family transcriptional regulator-
M6E97_RS13450 (M6E97_13430)2913844..2914242-399WP_033990114.1NADH-quinone oxidoreductase subunit A-
M6E97_RS13455 (M6E97_13435)2914255..2914578-324WP_003102734.1multidrug efflux SMR transporter-
M6E97_RS13460 (M6E97_13440)2914909..2915370+462WP_003102736.1(2Fe-2S)-binding protein-
M6E97_RS13465 (M6E97_13445)2915375..2917570+2196WP_023875495.1xanthine dehydrogenase family protein molybdopterin-binding subunit-
M6E97_RS13470 (M6E97_13450)2917724..2918278+555WP_003117666.1helix-turn-helix transcriptional regulatorAntitoxin
M6E97_RS13475 (M6E97_13455)2918367..2918945+579WP_003110488.1HD domain-containing proteinToxin
M6E97_RS13480 (M6E97_13460)2919055..2920242-1188WP_003139884.1HlyD family efflux transporter periplasmic adaptor subunit-
M6E97_RS13485 (M6E97_13465)2920232..2922403-2172WP_003088105.1type I secretion system permease/ATPase-
M6E97_RS13490 (M6E97_13470)2922393..2923670-1278WP_003088104.1TolC family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(7-188)

Antitoxin

Cro/C1-type helix-turn-helix domain

(11-66)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21913.75 Da        Isoelectric Point: 5.3655

>T246388 WP_003110488.1 NZ_CP097857:2918367-2918945 [Pseudomonas sp. B111]
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDTPLRDRLLALWDEYERGETAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA

Download         Length: 579 bp

Antitoxin


Download         Length: 185 a.a.        Molecular weight: 20454.67 Da        Isoelectric Point: 8.5356

>AT246388 WP_003117666.1 NZ_CP097857:2917724-2918278 [Pseudomonas sp. B111]
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADKALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL

Download         Length: 555 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0H2Z8V4

Antitoxin

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Source
ID
Structure
No matching records found

References