Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 2007512..2009016 Replicon chromosome
Accession NZ_CP097857
Organism Pseudomonas sp. B111

Toxin (Protein)


Gene name - Uniprot ID Q9HYX1
Locus tag M6E97_RS09630 Protein ID WP_003119682.1
Coordinates 2008429..2009016 (-) Length 196 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A9E8LAI1
Locus tag M6E97_RS09625 Protein ID WP_003117606.1
Coordinates 2007512..2008366 (-) Length 285 a.a.

Genomic Context


M6E97_RS09610M6E97_RS09635M6E97_RS09615M6E97_RS09620M6E97_RS09625M6E97_RS09630
Location: 2002931..2003140 (210 bp)
Type: Others
Protein ID: WP_003091604.1
Location: 2009282..2012761 (3480 bp)
Type: Others
Protein ID: WP_033938798.1
Location: 2003201..2005075 (1875 bp)
Type: Others
Protein ID: WP_003117607.1
Location: 2005250..2007415 (2166 bp)
Type: Others
Protein ID: WP_033989266.1
Location: 2007512..2008366 (855 bp)
Type: Antitoxin
Protein ID: WP_003117606.1
Location: 2008429..2009016 (588 bp)
Type: Toxin
Protein ID: WP_003119682.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M6E97_RS09610 (M6E97_09605)2002931..2003140+210WP_003091604.1cold-shock protein-
M6E97_RS09615 (M6E97_09610)2003201..2005075-1875WP_003117607.1MFS transporter-
M6E97_RS09620 (M6E97_09615)2005250..2007415-2166WP_033989266.1TonB-dependent receptor family protein-
M6E97_RS09625 (M6E97_09620)2007512..2008366-855WP_003117606.1AraC family transcriptional regulatorAntitoxin
M6E97_RS09630 (M6E97_09625)2008429..2009016-588WP_003119682.1GNAT family proteinToxin
M6E97_RS09635 (M6E97_09630)2009282..2012761+3480WP_033938798.1PAS domain-containing hybrid sensor histidine kinase/response regulator-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(20-152)

Antitoxin

(19-151)


Sequences


Toxin        


Download         Length: 196 a.a.        Molecular weight: 21901.23 Da        Isoelectric Point: 9.8676

>T246387 WP_003119682.1 NZ_CP097857:c2009016-2008429 [Pseudomonas sp. B111]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG

Download         Length: 588 bp


Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31863.14 Da        Isoelectric Point: 7.5295

>AT246387 WP_003117606.1 NZ_CP097857:c2008366-2007512 [Pseudomonas sp. B111]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE

Download         Length: 855 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
PDB1YRE
PDB8GXJ


Antitoxin

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Source
ID
Structure
No matching records found

References