Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 2007512..2009016 Replicon chromosome
Accession NZ_CP097857
Organism Pseudomonas sp. B111

Toxin (Protein)


Gene name - Uniprot ID Q9HYX1
Locus tag M6E97_RS09630 Protein ID WP_003119682.1
Coordinates 2008429..2009016 (-) Length 196 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A9E8LAI1
Locus tag M6E97_RS09625 Protein ID WP_003117606.1
Coordinates 2007512..2008366 (-) Length 285 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M6E97_RS09610 (M6E97_09605) 2002931..2003140 + 210 WP_003091604.1 cold-shock protein -
M6E97_RS09615 (M6E97_09610) 2003201..2005075 - 1875 WP_003117607.1 MFS transporter -
M6E97_RS09620 (M6E97_09615) 2005250..2007415 - 2166 WP_033989266.1 TonB-dependent receptor family protein -
M6E97_RS09625 (M6E97_09620) 2007512..2008366 - 855 WP_003117606.1 AraC family transcriptional regulator Antitoxin
M6E97_RS09630 (M6E97_09625) 2008429..2009016 - 588 WP_003119682.1 GNAT family protein Toxin
M6E97_RS09635 (M6E97_09630) 2009282..2012761 + 3480 WP_033938798.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(20-152)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-151)


Sequences

Toxin        


Download         Length: 196 a.a.        Molecular weight: 21901.23 Da        Isoelectric Point: 9.8676

>T246387 WP_003119682.1 NZ_CP097857:c2009016-2008429 [Pseudomonas sp. B111]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG

Download         Length: 588 bp

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31863.14 Da        Isoelectric Point: 7.5295

>AT246387 WP_003117606.1 NZ_CP097857:c2008366-2007512 [Pseudomonas sp. B111]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE

Download         Length: 855 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 1YRE
PDB 8GXJ

Antitoxin

Source ID Structure

References