Detailed information of TA system TA024637

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 5783361..5784022
• Replicon: chromosome
• Accession: NC_013947
• Organism: Stackebrandtia nassauensis DSM 44728

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: D3PVW0
• Locus tag: SNAS_RS26930
• Protein ID: WP_013020652.1
• Coordinates: 5783361..5783786 (-)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SNAS_RS35435
• Protein ID: WP_013020653.1
• Coordinates: 5783783..5784022 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

• Predicted DNA-binding protein, ribbon-helix-helix domain (2-39)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15569.73 Da
• Isoelectric Point: 4.2737

>T24637 WP_013020652.1 NC_013947:c5783786-5783361 [Stackebrandtia nassauensis DSM 44728]
VIVIADTSGILVAIDAAHELHDRGRRVFAHAETVLVTPMVLAEVDYLLTSRFGVQTALDFLDEINDGACVVYDVVDGDLR
AARELMAQYFDLAIGLTDAMNVVAADRWHTDRILTLDERHFRTVAPIHPELDAFTLLPVDG

Nucleotide

• Length: 426 bp

>T24637 NC_013947:c5783786-5783361 [Stackebrandtia nassauensis DSM 44728]
GTGATCGTGATCGCCGACACTTCCGGCATCCTCGTCGCCATCGACGCCGCCCACGAACTGCACGATCGAGGTCGGAGAGT
CTTCGCGCACGCCGAGACAGTCCTCGTGACGCCTATGGTGCTTGCGGAGGTCGACTATTTGTTGACCAGTCGATTCGGTG
TTCAAACCGCGCTGGACTTTCTTGACGAGATCAACGACGGCGCGTGCGTTGTCTACGACGTGGTTGATGGAGACCTGCGT
GCCGCGCGTGAGTTGATGGCCCAATACTTTGACCTGGCGATTGGACTGACTGACGCGATGAATGTCGTGGCTGCGGATCG
TTGGCATACCGATCGCATATTGACCCTTGATGAGCGCCATTTTCGAACGGTGGCGCCTATTCACCCGGAACTGGACGCGT
TCACGCTGCTACCCGTCGACGGATAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8516.67 Da
• Isoelectric Point: 10.5917

>AT24637 WP_013020653.1 NC_013947:c5784022-5783783 [Stackebrandtia nassauensis DSM 44728]
MKRTTVYLPEADAQLLKQVARRTGKSEAQLIREGVAHVLQAAPTRARGLRMVVNSGDPQWANRVDGELASGFGADGLSQ

Nucleotide

• Length: 240 bp

>AT24637 NC_013947:c5784022-5783783 [Stackebrandtia nassauensis DSM 44728]
ATGAAGCGAACAACGGTGTACCTGCCGGAAGCGGATGCCCAGCTGCTGAAACAGGTGGCACGCCGCACCGGAAAATCAGA
GGCGCAATTGATTCGTGAAGGTGTCGCTCATGTCCTTCAAGCCGCGCCCACTCGTGCACGCGGCTTGCGTATGGTCGTCA
ACAGCGGGGATCCTCAATGGGCGAATCGCGTGGATGGCGAATTGGCAAGTGGATTCGGTGCGGACGGCCTTTCGCAGTGA

Structures

Toxin

• AlphaFold DB: D3PVW0