Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 5783361..5784022 Replicon chromosome
Accession NC_013947
Organism Stackebrandtia nassauensis DSM 44728

Toxin (Protein)


Gene name vapC Uniprot ID D3PVW0
Locus tag SNAS_RS26930 Protein ID WP_013020652.1
Coordinates 5783361..5783786 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SNAS_RS35435 Protein ID WP_013020653.1
Coordinates 5783783..5784022 (-) Length 80 a.a.

Genomic Context

SNAS_RS26915SNAS_RS26920SNAS_RS26945SNAS_RS26950SNAS_RS26925SNAS_RS26930SNAS_RS35435SNAS_RS26935SNAS_RS26940SNAS_RS26955SNAS_RS26960
Location: 5780973..5782322 (1350 bp)
Type: Others
Protein ID: WP_013020649.1
Location: 5782412..5782936 (525 bp)
Type: Others
Protein ID: WP_013020650.1
Location: 5785400..5786032 (633 bp)
Type: Others
Protein ID: WP_013020656.1
Location: 5786038..5786604 (567 bp)
Type: Others
Protein ID: WP_013020657.1
Location: 5782933..5783331 (399 bp)
Type: Others
Protein ID: WP_013020651.1
Location: 5783361..5783786 (426 bp)
Type: Toxin
Protein ID: WP_013020652.1
Location: 5783783..5784022 (240 bp)
Type: Antitoxin
Protein ID: WP_013020653.1
Location: 5784057..5784404 (348 bp)
Type: Others
Protein ID: WP_013020654.1
Location: 5784401..5785294 (894 bp)
Type: Others
Protein ID: WP_013020655.1
Location: 5786608..5787759 (1152 bp)
Type: Others
Protein ID: WP_211207254.1
Location: 5787816..5788838 (1023 bp)
Type: Others
Protein ID: WP_013020659.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SNAS_RS269155780973..5782322+1350WP_013020649.1erythromycin esterase family protein-
SNAS_RS269205782412..5782936+525WP_013020650.1DUF1697 domain-containing protein-
SNAS_RS269255782933..5783331-399WP_013020651.1hypothetical protein-
SNAS_RS269305783361..5783786-426WP_013020652.1PIN domain-containing proteinToxin
SNAS_RS354355783783..5784022-240WP_013020653.1ribbon-helix-helix domain-containing proteinAntitoxin
SNAS_RS269355784057..5784404-348WP_013020654.1histidine triad nucleotide-binding protein-
SNAS_RS269405784401..5785294-894WP_013020655.1LysR family transcriptional regulator-
SNAS_RS269455785400..5786032+633WP_013020656.1dihydrofolate reductase family protein-
SNAS_RS269505786038..5786604+567WP_013020657.1hypothetical protein-
SNAS_RS269555786608..5787759-1152WP_211207254.1molecular chaperone DnaJ-
SNAS_RS269605787816..5788838-1023WP_013020659.1heat-inducible transcriptional repressor HrcA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

Predicted DNA-binding protein, ribbon-helix-helix domain

(2-39)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15569.73 Da        Isoelectric Point: 4.2737

>T24637 WP_013020652.1 NC_013947:c5783786-5783361 [Stackebrandtia nassauensis DSM 44728]
VIVIADTSGILVAIDAAHELHDRGRRVFAHAETVLVTPMVLAEVDYLLTSRFGVQTALDFLDEINDGACVVYDVVDGDLR
AARELMAQYFDLAIGLTDAMNVVAADRWHTDRILTLDERHFRTVAPIHPELDAFTLLPVDG

Download         Length: 426 bp

>T24637 NC_013947:c5783786-5783361 [Stackebrandtia nassauensis DSM 44728]
GTGATCGTGATCGCCGACACTTCCGGCATCCTCGTCGCCATCGACGCCGCCCACGAACTGCACGATCGAGGTCGGAGAGT
CTTCGCGCACGCCGAGACAGTCCTCGTGACGCCTATGGTGCTTGCGGAGGTCGACTATTTGTTGACCAGTCGATTCGGTG
TTCAAACCGCGCTGGACTTTCTTGACGAGATCAACGACGGCGCGTGCGTTGTCTACGACGTGGTTGATGGAGACCTGCGT
GCCGCGCGTGAGTTGATGGCCCAATACTTTGACCTGGCGATTGGACTGACTGACGCGATGAATGTCGTGGCTGCGGATCG
TTGGCATACCGATCGCATATTGACCCTTGATGAGCGCCATTTTCGAACGGTGGCGCCTATTCACCCGGAACTGGACGCGT
TCACGCTGCTACCCGTCGACGGATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8516.67 Da        Isoelectric Point: 10.5917

>AT24637 WP_013020653.1 NC_013947:c5784022-5783783 [Stackebrandtia nassauensis DSM 44728]
MKRTTVYLPEADAQLLKQVARRTGKSEAQLIREGVAHVLQAAPTRARGLRMVVNSGDPQWANRVDGELASGFGADGLSQ

Download         Length: 240 bp

>AT24637 NC_013947:c5784022-5783783 [Stackebrandtia nassauensis DSM 44728]
ATGAAGCGAACAACGGTGTACCTGCCGGAAGCGGATGCCCAGCTGCTGAAACAGGTGGCACGCCGCACCGGAAAATCAGA
GGCGCAATTGATTCGTGAAGGTGTCGCTCATGTCCTTCAAGCCGCGCCCACTCGTGCACGCGGCTTGCGTATGGTCGTCA
ACAGCGGGGATCCTCAATGGGCGAATCGCGTGGATGGCGAATTGGCAAGTGGATTCGGTGCGGACGGCCTTTCGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBD3PVW0

Antitoxin

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Source
ID
Structure
No matching records found

References