Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
Location | 2904301..2904535 | Replicon | chromosome |
Accession | NZ_CP097840 | ||
Organism | Shigella flexneri strain A |
Toxin (RNA)
Gene name | SdsR | ||
Locus tag | - | ||
Coordinates | 2904431..2904534 (+) |
Antitoxin (RNA)
Gene name | RyeA | ||
Locus tag | - | ||
Coordinates | 2904301..2904535 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M9382_RS14285 | 2900856..2901518 | - | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
M9382_RS14290 | 2901542..2902198 | - | 657 | Protein_2771 | carbon-nitrogen hydrolase family protein YobB | - |
M9382_RS14295 | 2902300..2902530 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
M9382_RS14300 | 2902669..2903043 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
M9382_RS14305 | 2903047..2903919 | + | 873 | Protein_2774 | copper homeostasis membrane protein CopD | - |
M9382_RS14310 | 2903932..2904273 | + | 342 | WP_000976476.1 | YebY family protein | - |
- | 2904301..2904535 | - | 235 | - | - | Antitoxin |
- | 2904431..2904534 | + | 104 | - | - | Toxin |
M9382_RS14315 | 2904666..2905742 | - | 1077 | Protein_2776 | phage integrase Arm DNA-binding domain-containing protein | - |
M9382_RS14320 | 2905708..2905989 | - | 282 | WP_005127484.1 | excisionase | - |
M9382_RS14325 | 2906106..2906954 | - | 849 | Protein_2778 | IS3-like element IS600 family transposase | - |
M9382_RS14330 | 2907009..2908218 | + | 1210 | Protein_2779 | IS3 family transposase | - |
M9382_RS14335 | 2908261..2908571 | - | 311 | Protein_2780 | transposase | - |
M9382_RS14340 | 2908635..2909102 | + | 468 | Protein_2781 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | ipaH9.8 | 2851182..2915259 | 64077 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T246365 NZ_CP097840:2904431-2904534 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT246365 NZ_CP097840:c2904535-2904301 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT