Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2904301..2904535 Replicon chromosome
Accession NZ_CP097840
Organism Shigella flexneri strain A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2904431..2904534 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2904301..2904535 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9382_RS14285 2900856..2901518 - 663 WP_000944271.1 exodeoxyribonuclease X -
M9382_RS14290 2901542..2902198 - 657 Protein_2771 carbon-nitrogen hydrolase family protein YobB -
M9382_RS14295 2902300..2902530 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M9382_RS14300 2902669..2903043 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M9382_RS14305 2903047..2903919 + 873 Protein_2774 copper homeostasis membrane protein CopD -
M9382_RS14310 2903932..2904273 + 342 WP_000976476.1 YebY family protein -
- 2904301..2904535 - 235 - - Antitoxin
- 2904431..2904534 + 104 - - Toxin
M9382_RS14315 2904666..2905742 - 1077 Protein_2776 phage integrase Arm DNA-binding domain-containing protein -
M9382_RS14320 2905708..2905989 - 282 WP_005127484.1 excisionase -
M9382_RS14325 2906106..2906954 - 849 Protein_2778 IS3-like element IS600 family transposase -
M9382_RS14330 2907009..2908218 + 1210 Protein_2779 IS3 family transposase -
M9382_RS14335 2908261..2908571 - 311 Protein_2780 transposase -
M9382_RS14340 2908635..2909102 + 468 Protein_2781 DNA-binding transcriptional regulator PgrR -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2851182..2915259 64077


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246365 NZ_CP097840:2904431-2904534 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT246365 NZ_CP097840:c2904535-2904301 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References