Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2389291..2389525 | Replicon | chromosome |
| Accession | NZ_CP097837 | ||
| Organism | Shigella flexneri strain B | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2389292..2389395 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2389291..2389525 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M9380_RS12095 | 2384724..2385191 | - | 468 | Protein_2352 | DNA-binding transcriptional regulator PgrR | - |
| M9380_RS12100 | 2385255..2385565 | + | 311 | Protein_2353 | transposase | - |
| M9380_RS12105 | 2385608..2386817 | - | 1210 | Protein_2354 | IS3 family transposase | - |
| M9380_RS12110 | 2386872..2387720 | + | 849 | Protein_2355 | IS3-like element IS600 family transposase | - |
| M9380_RS12115 | 2387837..2388118 | + | 282 | WP_005127484.1 | excisionase | - |
| M9380_RS12120 | 2388084..2389160 | + | 1077 | Protein_2357 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2389291..2389525 | + | 235 | - | - | Antitoxin |
| - | 2389292..2389395 | - | 104 | - | - | Toxin |
| M9380_RS12125 | 2389553..2389894 | - | 342 | WP_000976476.1 | YebY family protein | - |
| M9380_RS12130 | 2389907..2390779 | - | 873 | Protein_2359 | copper homeostasis membrane protein CopD | - |
| M9380_RS12135 | 2390783..2391157 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| M9380_RS12140 | 2391296..2391526 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| M9380_RS12145 | 2391628..2392284 | + | 657 | Protein_2362 | carbon-nitrogen hydrolase family protein YobB | - |
| M9380_RS12150 | 2392308..2392970 | + | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T246346 NZ_CP097837:c2389395-2389292 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT246346 NZ_CP097837:2389291-2389525 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
