Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 861094..861328 | Replicon | chromosome |
| Accession | NZ_CP097834 | ||
| Organism | Shigella flexneri strain C | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 861224..861327 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 861094..861328 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M9379_RS04355 | 857649..858311 | - | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
| M9379_RS04360 | 858335..858991 | - | 657 | Protein_843 | carbon-nitrogen hydrolase family protein YobB | - |
| M9379_RS04365 | 859093..859323 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| M9379_RS04370 | 859462..859836 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| M9379_RS04375 | 859840..860712 | + | 873 | Protein_846 | copper homeostasis membrane protein CopD | - |
| M9379_RS04380 | 860725..861066 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 861094..861328 | - | 235 | - | - | Antitoxin |
| - | 861224..861327 | + | 104 | - | - | Toxin |
| M9379_RS04385 | 861459..862535 | - | 1077 | Protein_848 | phage integrase Arm DNA-binding domain-containing protein | - |
| M9379_RS04390 | 862501..862782 | - | 282 | WP_005127484.1 | excisionase | - |
| M9379_RS04395 | 862899..863747 | - | 849 | Protein_850 | IS3-like element IS600 family transposase | - |
| M9379_RS04400 | 863802..865011 | + | 1210 | Protein_851 | IS3 family transposase | - |
| M9379_RS04405 | 865054..865364 | - | 311 | Protein_852 | transposase | - |
| M9379_RS04410 | 865428..865895 | + | 468 | Protein_853 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 807975..872052 | 64077 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T246320 NZ_CP097834:861224-861327 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT246320 NZ_CP097834:c861328-861094 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
