Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2905125..2905359 | Replicon | chromosome |
| Accession | NZ_CP097831 | ||
| Organism | Shigella flexneri strain D | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2905255..2905358 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2905125..2905359 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M9381_RS14300 | 2901680..2902342 | - | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
| M9381_RS14305 | 2902366..2903022 | - | 657 | Protein_2774 | carbon-nitrogen hydrolase family protein YobB | - |
| M9381_RS14310 | 2903124..2903354 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| M9381_RS14315 | 2903493..2903867 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| M9381_RS14320 | 2903871..2904743 | + | 873 | Protein_2777 | copper homeostasis membrane protein CopD | - |
| M9381_RS14325 | 2904756..2905097 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2905125..2905359 | - | 235 | - | - | Antitoxin |
| - | 2905255..2905358 | + | 104 | - | - | Toxin |
| M9381_RS14330 | 2905490..2906566 | - | 1077 | Protein_2779 | phage integrase Arm DNA-binding domain-containing protein | - |
| M9381_RS14335 | 2906532..2906813 | - | 282 | WP_005127484.1 | excisionase | - |
| M9381_RS14340 | 2906930..2907778 | - | 849 | Protein_2781 | IS3-like element IS600 family transposase | - |
| M9381_RS14345 | 2907833..2909042 | + | 1210 | Protein_2782 | IS3 family transposase | - |
| M9381_RS14350 | 2909085..2909395 | - | 311 | Protein_2783 | transposase | - |
| M9381_RS14355 | 2909459..2909926 | + | 468 | Protein_2784 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T246304 NZ_CP097831:2905255-2905358 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT246304 NZ_CP097831:c2905359-2905125 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
