Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4485274..4485508 | Replicon | chromosome |
| Accession | NZ_CP097828 | ||
| Organism | Shigella flexneri strain E | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4485275..4485378 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4485274..4485508 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M9383_RS22590 | 4480707..4481174 | - | 468 | Protein_4393 | DNA-binding transcriptional regulator PgrR | - |
| M9383_RS22595 | 4481238..4481548 | + | 311 | Protein_4394 | transposase | - |
| M9383_RS22600 | 4481591..4482800 | - | 1210 | Protein_4395 | IS3 family transposase | - |
| M9383_RS22605 | 4482855..4483703 | + | 849 | Protein_4396 | IS3-like element IS600 family transposase | - |
| M9383_RS22610 | 4483820..4484101 | + | 282 | WP_005127484.1 | excisionase | - |
| M9383_RS22615 | 4484067..4485143 | + | 1077 | Protein_4398 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4485274..4485508 | + | 235 | - | - | Antitoxin |
| - | 4485275..4485378 | - | 104 | - | - | Toxin |
| M9383_RS22620 | 4485536..4485877 | - | 342 | WP_000976476.1 | YebY family protein | - |
| M9383_RS22625 | 4485890..4486762 | - | 873 | Protein_4400 | copper homeostasis membrane protein CopD | - |
| M9383_RS22630 | 4486766..4487140 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| M9383_RS22635 | 4487279..4487509 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| M9383_RS22640 | 4487611..4488267 | + | 657 | Protein_4403 | carbon-nitrogen hydrolase family protein YobB | - |
| M9383_RS22645 | 4488291..4488953 | + | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 4474550..4508304 | 33754 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T246290 NZ_CP097828:c4485378-4485275 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT246290 NZ_CP097828:4485274-4485508 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
