Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1937255..1937399 Replicon chromosome
Accession NZ_CP097808
Organism Klebsiella variicola strain 17YN56

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1937291..1937393 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1937255..1937399 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9O80_RS09405 (M9O80_09405) 1932385..1934445 + 2061 WP_070612270.1 oligopeptidase B -
M9O80_RS09410 (M9O80_09410) 1934449..1935108 - 660 WP_008804267.1 exodeoxyribonuclease X -
M9O80_RS09415 (M9O80_09415) 1935187..1935417 - 231 WP_012541260.1 DNA polymerase III subunit theta -
M9O80_RS09420 (M9O80_09420) 1935531..1935905 + 375 WP_012541261.1 CopC domain-containing protein YobA -
M9O80_RS09425 (M9O80_09425) 1935909..1936778 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
M9O80_RS09430 (M9O80_09430) 1936795..1937133 + 339 WP_008804271.1 YebY family protein -
- 1937255..1937399 - 145 - - Antitoxin
- 1937291..1937393 + 103 - - Toxin
M9O80_RS09435 (M9O80_09435) 1937778..1937921 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
M9O80_RS09440 (M9O80_09440) 1938025..1938993 - 969 WP_162493241.1 VirK/YbjX family protein -
M9O80_RS09445 (M9O80_09445) 1939150..1939803 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
M9O80_RS09450 (M9O80_09450) 1939800..1939991 - 192 WP_002911395.1 YebW family protein -
M9O80_RS09455 (M9O80_09455) 1940089..1940328 - 240 WP_002911393.1 YebV family protein -
M9O80_RS09460 (M9O80_09460) 1940444..1941877 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246266 NZ_CP097808:1937291-1937393 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT246266 NZ_CP097808:c1937399-1937255 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References