Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 405396..406024 Replicon chromosome
Accession NZ_CP097807
Organism Thalassospira sp. GO-4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M9H61_RS01985 Protein ID WP_250283071.1
Coordinates 405396..405794 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M9H61_RS01990 Protein ID WP_228195922.1
Coordinates 405794..406024 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9H61_RS01975 (M9H61_01975) 401415..404222 - 2808 WP_250283067.1 ribosome-associated ATPase/putative transporter RbbA -
M9H61_RS01980 (M9H61_01980) 404222..405232 - 1011 WP_250283069.1 efflux RND transporter periplasmic adaptor subunit -
M9H61_RS01985 (M9H61_01985) 405396..405794 - 399 WP_250283071.1 tRNA(fMet)-specific endonuclease VapC Toxin
M9H61_RS01990 (M9H61_01990) 405794..406024 - 231 WP_228195922.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
M9H61_RS01995 (M9H61_01995) 406112..406462 - 351 WP_250283073.1 Dabb family protein -
M9H61_RS02000 (M9H61_02000) 406501..407805 - 1305 WP_250283075.1 aspartate aminotransferase family protein -
M9H61_RS02005 (M9H61_02005) 407926..408849 + 924 WP_250283077.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14851.00 Da        Isoelectric Point: 6.8629

>T246257 WP_250283071.1 NZ_CP097807:c405794-405396 [Thalassospira sp. GO-4]
MLRFMLDTNICIYVIKNRPASCREKFRTHSGAMAISSVTLAELIYGAMKSAKPESNLRTIEEFAARLSVLDFDTDAAGHY
GDIRSTLEREGNVIGPYDMMIAGHARSHGLILVTNNTREFERVDGLRLENWV

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8540.56 Da        Isoelectric Point: 4.4685

>AT246257 WP_228195922.1 NZ_CP097807:c406024-405794 [Thalassospira sp. GO-4]
MTQASVFLNNKTQAVRLPKDVAFPEGTKTVEVISVGVTRVIVPSDHLWDTFFDGHAVSDDFMEDRNQPAMQERDGF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References