Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3857744..3859263 Replicon chromosome
Accession NZ_CP097804
Organism Xanthomonas oryzae pv. oryzae strain FY517

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag M9500_RS18400 Protein ID WP_011259680.1
Coordinates 3858340..3859263 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag M9500_RS18395 Protein ID WP_011409027.1
Coordinates 3857744..3858343 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9500_RS18360 (M9500_18360) 3853426..3853962 - 537 WP_011409032.1 lipocalin family protein -
M9500_RS18370 (M9500_18370) 3854232..3854699 - 468 WP_181718264.1 hypothetical protein -
M9500_RS18375 (M9500_18375) 3854680..3854970 - 291 WP_011409031.1 hypothetical protein -
M9500_RS18380 (M9500_18380) 3855469..3856500 + 1032 WP_042465093.1 IS630 family transposase -
M9500_RS18385 (M9500_18385) 3856482..3857057 - 576 WP_011409029.1 BrxE family protein -
M9500_RS18390 (M9500_18390) 3857089..3857379 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
M9500_RS18395 (M9500_18395) 3857744..3858343 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
M9500_RS18400 (M9500_18400) 3858340..3859263 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
M9500_RS18405 (M9500_18405) 3859343..3859813 - 471 WP_228383551.1 helix-turn-helix domain-containing protein -
M9500_RS18410 (M9500_18410) 3860279..3860521 + 243 WP_011409025.1 hypothetical protein -
M9500_RS18415 (M9500_18415) 3860973..3861938 - 966 Protein_3516 IS1595-like element ISXo5 family transposase -
M9500_RS18420 (M9500_18420) 3862033..3862521 + 489 WP_011409022.1 hypothetical protein -
M9500_RS18425 (M9500_18425) 3862538..3863070 - 533 Protein_3518 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T246255 WP_011259680.1 NZ_CP097804:3858340-3859263 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT246255 WP_011409027.1 NZ_CP097804:3857744-3858343 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References