Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2149020..2149291 Replicon chromosome
Accession NZ_CP097726
Organism Escherichia coli strain MS1050

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2149150..2149253 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2149020..2149291 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9O78_RS10105 2145575..2146237 - 663 WP_000944256.1 exodeoxyribonuclease X -
M9O78_RS10110 2146261..2146917 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
M9O78_RS10115 2147019..2147249 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M9O78_RS10120 2147388..2147762 + 375 WP_000204705.1 CopC domain-containing protein YobA -
M9O78_RS10125 2147766..2148638 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
M9O78_RS10130 2148651..2148992 + 342 WP_000976481.1 YebY family protein -
- 2149020..2149291 - 272 - - Antitoxin
- 2149150..2149253 + 104 - - Toxin
M9O78_RS10135 2149388..2150044 + 657 WP_001546849.1 protein-serine/threonine phosphatase -
M9O78_RS10140 2150045..2150236 - 192 WP_001296140.1 YebW family protein -
M9O78_RS10145 2150341..2150577 - 237 WP_001295499.1 YebV family protein -
M9O78_RS10150 2150695..2152134 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2141710..2165841 24131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246199 NZ_CP097726:2149150-2149253 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246199 NZ_CP097726:c2149291-2149020 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References