Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2205908..2206179 Replicon chromosome
Accession NZ_CP097716
Organism Escherichia coli strain MS1718

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2206038..2206141 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2205908..2206179 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9O77_RS10530 2202463..2203125 - 663 WP_000944256.1 exodeoxyribonuclease X -
M9O77_RS10535 2203149..2203805 - 657 WP_000011663.1 carbon-nitrogen hydrolase family protein YobB -
M9O77_RS10540 2203907..2204137 - 231 WP_077516099.1 DNA polymerase III subunit theta -
M9O77_RS10545 2204276..2204650 + 375 WP_000168737.1 CopC domain-containing protein YobA -
M9O77_RS10550 2204654..2205526 + 873 WP_000879323.1 copper homeostasis membrane protein CopD -
M9O77_RS10555 2205539..2205880 + 342 WP_000976472.1 YebY family protein -
- 2205908..2206179 - 272 - - Antitoxin
- 2206038..2206141 + 104 - - Toxin
M9O77_RS10560 2206276..2206932 + 657 WP_000812749.1 protein-serine/threonine phosphatase -
M9O77_RS10565 2206933..2207124 - 192 WP_001296140.1 YebW family protein -
M9O77_RS10570 2207229..2207465 - 237 WP_001295499.1 YebV family protein -
M9O77_RS10575 2207583..2209022 - 1440 WP_024175799.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2164366..2222019 57653


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246089 NZ_CP097716:2206038-2206141 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246089 NZ_CP097716:c2206179-2205908 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References