Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1977085..1977230 Replicon chromosome
Accession NZ_CP097697
Organism Klebsiella pneumoniae strain IR12183_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1977121..1977223 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1977085..1977230 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X92_RS09740 (M3X92_09740) 1972215..1974275 + 2061 WP_004151449.1 oligopeptidase B -
M3X92_RS09745 (M3X92_09745) 1974279..1974938 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X92_RS09750 (M3X92_09750) 1975017..1975247 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X92_RS09755 (M3X92_09755) 1975360..1975734 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X92_RS09760 (M3X92_09760) 1975738..1976607 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X92_RS09765 (M3X92_09765) 1976624..1976962 + 339 WP_002911404.1 YebY family protein -
- 1977085..1977230 - 146 - - Antitoxin
- 1977121..1977223 + 103 - - Toxin
M3X92_RS09770 (M3X92_09770) 1977598..1977741 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X92_RS09775 (M3X92_09775) 1977846..1978814 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X92_RS09780 (M3X92_09780) 1978971..1979624 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X92_RS09785 (M3X92_09785) 1979621..1979812 - 192 WP_002911395.1 YebW family protein -
M3X92_RS09790 (M3X92_09790) 1979910..1980149 - 240 WP_002911393.1 YebV family protein -
M3X92_RS09795 (M3X92_09795) 1980265..1981698 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246005 NZ_CP097697:1977121-1977223 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246005 NZ_CP097697:c1977230-1977085 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References