Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994568..1994713 Replicon chromosome
Accession NZ_CP097694
Organism Klebsiella pneumoniae strain IR12182_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994604..1994706 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994568..1994713 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X85_RS09770 (M3X85_09770) 1989698..1991758 + 2061 WP_004151449.1 oligopeptidase B -
M3X85_RS09775 (M3X85_09775) 1991762..1992421 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X85_RS09780 (M3X85_09780) 1992500..1992730 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X85_RS09785 (M3X85_09785) 1992843..1993217 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X85_RS09790 (M3X85_09790) 1993221..1994090 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X85_RS09795 (M3X85_09795) 1994107..1994445 + 339 WP_002911404.1 YebY family protein -
- 1994568..1994713 - 146 - - Antitoxin
- 1994604..1994706 + 103 - - Toxin
M3X85_RS09800 (M3X85_09800) 1995081..1995224 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X85_RS09805 (M3X85_09805) 1995329..1996297 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X85_RS09810 (M3X85_09810) 1996454..1997107 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X85_RS09815 (M3X85_09815) 1997104..1997295 - 192 WP_002911395.1 YebW family protein -
M3X85_RS09820 (M3X85_09820) 1997393..1997632 - 240 WP_002911393.1 YebV family protein -
M3X85_RS09825 (M3X85_09825) 1997748..1999181 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245981 NZ_CP097694:1994604-1994706 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245981 NZ_CP097694:c1994713-1994568 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References