Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2068396..2068541 Replicon chromosome
Accession NZ_CP097692
Organism Klebsiella pneumoniae strain IR12094_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2068432..2068534 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2068396..2068541 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3T51_RS10190 (M3T51_10190) 2063526..2065586 + 2061 WP_004151449.1 oligopeptidase B -
M3T51_RS10195 (M3T51_10195) 2065590..2066249 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3T51_RS10200 (M3T51_10200) 2066328..2066558 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3T51_RS10205 (M3T51_10205) 2066671..2067045 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3T51_RS10210 (M3T51_10210) 2067049..2067918 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3T51_RS10215 (M3T51_10215) 2067935..2068273 + 339 WP_002911404.1 YebY family protein -
- 2068396..2068541 - 146 - - Antitoxin
- 2068432..2068534 + 103 - - Toxin
M3T51_RS10220 (M3T51_10220) 2068909..2069052 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3T51_RS10225 (M3T51_10225) 2069157..2070125 - 969 WP_004151446.1 VirK/YbjX family protein -
M3T51_RS10230 (M3T51_10230) 2070282..2070935 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3T51_RS10235 (M3T51_10235) 2070932..2071123 - 192 WP_002911395.1 YebW family protein -
M3T51_RS10240 (M3T51_10240) 2071221..2071460 - 240 WP_002911393.1 YebV family protein -
M3T51_RS10245 (M3T51_10245) 2071576..2073009 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245960 NZ_CP097692:2068432-2068534 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245960 NZ_CP097692:c2068541-2068396 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References