Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2107617..2107762 Replicon chromosome
Accession NZ_CP097688
Organism Klebsiella pneumoniae strain IR12079_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2107653..2107755 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2107617..2107762 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X89_RS10505 (M3X89_10505) 2102747..2104807 + 2061 WP_004151449.1 oligopeptidase B -
M3X89_RS10510 (M3X89_10510) 2104811..2105470 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X89_RS10515 (M3X89_10515) 2105549..2105779 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X89_RS10520 (M3X89_10520) 2105892..2106266 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X89_RS10525 (M3X89_10525) 2106270..2107139 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X89_RS10530 (M3X89_10530) 2107156..2107494 + 339 WP_002911404.1 YebY family protein -
- 2107617..2107762 - 146 - - Antitoxin
- 2107653..2107755 + 103 - - Toxin
M3X89_RS10535 (M3X89_10535) 2108130..2108273 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X89_RS10540 (M3X89_10540) 2108378..2109346 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X89_RS10545 (M3X89_10545) 2109503..2110156 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X89_RS10550 (M3X89_10550) 2110153..2110344 - 192 WP_002911395.1 YebW family protein -
M3X89_RS10555 (M3X89_10555) 2110442..2110681 - 240 WP_002911393.1 YebV family protein -
M3X89_RS10560 (M3X89_10560) 2110797..2112230 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245935 NZ_CP097688:2107653-2107755 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245935 NZ_CP097688:c2107762-2107617 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References