Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2090882..2091027 Replicon chromosome
Accession NZ_CP097683
Organism Klebsiella pneumoniae strain IR12073_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2090918..2091020 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2090882..2091027 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X91_RS10275 (M3X91_10275) 2086012..2088072 + 2061 WP_004151449.1 oligopeptidase B -
M3X91_RS10280 (M3X91_10280) 2088076..2088735 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X91_RS10285 (M3X91_10285) 2088814..2089044 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X91_RS10290 (M3X91_10290) 2089157..2089531 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X91_RS10295 (M3X91_10295) 2089535..2090404 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X91_RS10300 (M3X91_10300) 2090421..2090759 + 339 WP_002911404.1 YebY family protein -
- 2090882..2091027 - 146 - - Antitoxin
- 2090918..2091020 + 103 - - Toxin
M3X91_RS10305 (M3X91_10305) 2091395..2091538 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X91_RS10310 (M3X91_10310) 2091643..2092611 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X91_RS10315 (M3X91_10315) 2092768..2093421 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X91_RS10320 (M3X91_10320) 2093418..2093609 - 192 WP_002911395.1 YebW family protein -
M3X91_RS10325 (M3X91_10325) 2093707..2093946 - 240 WP_002911393.1 YebV family protein -
M3X91_RS10330 (M3X91_10330) 2094062..2095495 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245912 NZ_CP097683:2090918-2091020 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245912 NZ_CP097683:c2091027-2090882 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References