Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029897..2030042 Replicon chromosome
Accession NZ_CP097670
Organism Klebsiella pneumoniae strain IR5077_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029933..2030035 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029897..2030042 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X94_RS09930 (M3X94_09930) 2025027..2027087 + 2061 WP_004151449.1 oligopeptidase B -
M3X94_RS09935 (M3X94_09935) 2027091..2027750 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X94_RS09940 (M3X94_09940) 2027829..2028059 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X94_RS09945 (M3X94_09945) 2028172..2028546 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X94_RS09950 (M3X94_09950) 2028550..2029419 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X94_RS09955 (M3X94_09955) 2029436..2029774 + 339 WP_002911404.1 YebY family protein -
- 2029897..2030042 - 146 - - Antitoxin
- 2029933..2030035 + 103 - - Toxin
M3X94_RS09960 (M3X94_09960) 2030410..2030553 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X94_RS09965 (M3X94_09965) 2030658..2031626 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X94_RS09970 (M3X94_09970) 2031783..2032436 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X94_RS09975 (M3X94_09975) 2032433..2032624 - 192 WP_002911395.1 YebW family protein -
M3X94_RS09980 (M3X94_09980) 2032722..2032961 - 240 WP_002911393.1 YebV family protein -
M3X94_RS09985 (M3X94_09985) 2033077..2034510 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245842 NZ_CP097670:2029933-2030035 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245842 NZ_CP097670:c2030042-2029897 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References