Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1584920..1585540 Replicon chromosome
Accession NC_013892
Organism Xenorhabdus bovienii SS-2004

Toxin (Protein)


Gene name Hha Uniprot ID N1NUC1
Locus tag XBJ1_RS06965 Protein ID WP_010845060.1
Coordinates 1585337..1585540 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag XBJ1_RS06960 Protein ID WP_038198607.1
Coordinates 1584920..1585288 (+) Length 123 a.a.

Genomic Context

XBJ1_RS06950XBJ1_RS06955XBJ1_RS06960XBJ1_RS06965XBJ1_RS06970XBJ1_RS06975XBJ1_RS06980
Location: 1579950..1581149 (1200 bp)
Type: Others
Protein ID: WP_012988120.1
Location: 1581165..1584314 (3150 bp)
Type: Others
Protein ID: WP_012988121.1
Location: 1584920..1585288 (369 bp)
Type: Antitoxin
Protein ID: WP_038198607.1
Location: 1585337..1585540 (204 bp)
Type: Toxin
Protein ID: WP_010845060.1
Location: 1586594..1587886 (1293 bp)
Type: Others
Protein ID: WP_012988124.1
Location: 1587902..1588240 (339 bp)
Type: Others
Protein ID: WP_038198610.1
Location: 1588408..1590177 (1770 bp)
Type: Others
Protein ID: WP_143827722.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XBJ1_RS069501579950..1581149+1200WP_012988120.1efflux RND transporter periplasmic adaptor subunit-
XBJ1_RS069551581165..1584314+3150WP_012988121.1multidrug efflux RND transporter permease subunit-
XBJ1_RS069601584920..1585288+369WP_038198607.1Hha toxicity modulator TomBAntitoxin
XBJ1_RS069651585337..1585540+204WP_010845060.1hemolysin expression modulator HhaToxin
XBJ1_RS069701586594..1587886-1293WP_012988124.1ammonium transporter AmtB-
XBJ1_RS069751587902..1588240-339WP_038198610.1P-II family nitrogen regulator-
XBJ1_RS069801588408..1590177-1770WP_143827722.1SmdB family multidrug efflux ABC transporter permease/ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8077.34 Da        Isoelectric Point: 6.9770

>T24582 WP_010845060.1 NC_013892:1585337-1585540 [Xenorhabdus bovienii SS-2004]
MTKTDYLMRLRKCTSIETLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPSSVWKFVR

Download         Length: 204 bp

>T24582 NC_013892:1585337-1585540 [Xenorhabdus bovienii SS-2004]
ATGACTAAAACTGACTATCTGATGCGTTTGAGAAAATGCACTTCTATTGAAACACTGGAACGTGTAATTGAAAAAAATAA
ATATGAGCTTTCGGATGATGAACTTGAATTGTTCTACTCTGCTGCTGACCACCGCTTAGCTGAACTTACTATGAATAAGC
TTTATGATAAGATCCCATCATCTGTTTGGAAATTTGTCCGCTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14440.36 Da        Isoelectric Point: 5.5225

>AT24582 WP_038198607.1 NC_013892:1584920-1585288 [Xenorhabdus bovienii SS-2004]
MDEYSPRRHDIVELKYLCENLIHEAFSVLNRADNHWINDLTSEKSLKLNELIEHIAAFVWSFKIKYADNYNLSTLIDKYL
DETYNLFGSDKISCFELTKWQKTNEHLTNILLHDLNACLSKT

Download         Length: 369 bp

>AT24582 NC_013892:1584920-1585288 [Xenorhabdus bovienii SS-2004]
ATGGATGAATATTCACCAAGAAGACATGATATTGTTGAATTAAAATACTTATGTGAAAATTTAATTCACGAGGCATTTTC
AGTGCTAAATCGCGCTGATAATCATTGGATTAACGATCTGACTTCCGAAAAAAGCTTAAAACTAAATGAATTGATCGAGC
ACATTGCAGCGTTCGTCTGGAGTTTTAAAATTAAATACGCAGATAACTACAATCTCAGTACCTTAATTGATAAATACCTG
GATGAAACATATAATTTGTTCGGGAGTGATAAGATAAGCTGTTTTGAACTTACAAAATGGCAAAAAACAAACGAACACTT
AACTAACATTCTGTTGCATGATTTGAATGCCTGTTTAAGCAAAACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBN1NUC1

Antitoxin

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Source
ID
Structure
No matching records found

References