Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011297..2011442 Replicon chromosome
Accession NZ_CP097663
Organism Klebsiella pneumoniae strain IR1230_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011333..2011435 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011297..2011442 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X90_RS09890 (M3X90_09890) 2006427..2008487 + 2061 WP_004151449.1 oligopeptidase B -
M3X90_RS09895 (M3X90_09895) 2008491..2009150 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X90_RS09900 (M3X90_09900) 2009229..2009459 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X90_RS09905 (M3X90_09905) 2009572..2009946 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X90_RS09910 (M3X90_09910) 2009950..2010819 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X90_RS09915 (M3X90_09915) 2010836..2011174 + 339 WP_002911404.1 YebY family protein -
- 2011297..2011442 - 146 - - Antitoxin
- 2011333..2011435 + 103 - - Toxin
M3X90_RS09920 (M3X90_09920) 2011810..2011953 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X90_RS09925 (M3X90_09925) 2012058..2013026 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X90_RS09930 (M3X90_09930) 2013183..2013836 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X90_RS09935 (M3X90_09935) 2013833..2014024 - 192 WP_002911395.1 YebW family protein -
M3X90_RS09940 (M3X90_09940) 2014122..2014361 - 240 WP_002911393.1 YebV family protein -
M3X90_RS09945 (M3X90_09945) 2014477..2015910 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245813 NZ_CP097663:2011333-2011435 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245813 NZ_CP097663:c2011442-2011297 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References