Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011016..2011161 Replicon chromosome
Accession NZ_CP097660
Organism Klebsiella pneumoniae strain IR12243_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011052..2011154 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011016..2011161 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X86_RS09840 (M3X86_09840) 2006148..2008207 + 2060 Protein_1926 oligopeptidase B -
M3X86_RS09845 (M3X86_09845) 2008211..2008869 - 659 Protein_1927 exodeoxyribonuclease X -
M3X86_RS09850 (M3X86_09850) 2008948..2009178 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X86_RS09855 (M3X86_09855) 2009291..2009665 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X86_RS09860 (M3X86_09860) 2009669..2010538 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X86_RS09865 (M3X86_09865) 2010555..2010893 + 339 WP_002911404.1 YebY family protein -
- 2011016..2011161 - 146 - - Antitoxin
- 2011052..2011154 + 103 - - Toxin
M3X86_RS09870 (M3X86_09870) 2011529..2011672 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X86_RS09875 (M3X86_09875) 2011777..2012745 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X86_RS09880 (M3X86_09880) 2012902..2013555 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X86_RS09885 (M3X86_09885) 2013552..2013743 - 192 WP_002911395.1 YebW family protein -
M3X86_RS09890 (M3X86_09890) 2013841..2014080 - 240 WP_002911393.1 YebV family protein -
M3X86_RS09895 (M3X86_09895) 2014196..2015629 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245790 NZ_CP097660:2011052-2011154 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245790 NZ_CP097660:c2011161-2011016 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References