Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1999102..1999247 Replicon chromosome
Accession NZ_CP097658
Organism Klebsiella pneumoniae strain IR12099_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1999138..1999240 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1999102..1999247 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X93_RS09785 (M3X93_09785) 1994232..1996292 + 2061 WP_004151449.1 oligopeptidase B -
M3X93_RS09790 (M3X93_09790) 1996296..1996955 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X93_RS09795 (M3X93_09795) 1997034..1997264 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X93_RS09800 (M3X93_09800) 1997377..1997751 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X93_RS09805 (M3X93_09805) 1997755..1998624 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X93_RS09810 (M3X93_09810) 1998641..1998979 + 339 WP_002911404.1 YebY family protein -
- 1999102..1999247 - 146 - - Antitoxin
- 1999138..1999240 + 103 - - Toxin
M3X93_RS09815 (M3X93_09815) 1999613..1999756 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X93_RS09820 (M3X93_09820) 1999861..2000829 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X93_RS09825 (M3X93_09825) 2000986..2001639 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3X93_RS09830 (M3X93_09830) 2001636..2001827 - 192 WP_002911395.1 YebW family protein -
M3X93_RS09835 (M3X93_09835) 2001925..2002164 - 240 WP_002911393.1 YebV family protein -
M3X93_RS09840 (M3X93_09840) 2002280..2003713 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245768 NZ_CP097658:1999138-1999240 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245768 NZ_CP097658:c1999247-1999102 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References