Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4127096..4127241 Replicon chromosome
Accession NZ_CP097654
Organism Klebsiella pneumoniae strain IR1272_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4127132..4127234 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4127096..4127241 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3T50_RS20050 (M3T50_20050) 4122226..4124286 + 2061 WP_004151449.1 oligopeptidase B -
M3T50_RS20055 (M3T50_20055) 4124290..4124949 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3T50_RS20060 (M3T50_20060) 4125028..4125258 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3T50_RS20065 (M3T50_20065) 4125371..4125745 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3T50_RS20070 (M3T50_20070) 4125749..4126618 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3T50_RS20075 (M3T50_20075) 4126635..4126973 + 339 WP_002911404.1 YebY family protein -
- 4127096..4127241 - 146 - - Antitoxin
- 4127132..4127234 + 103 - - Toxin
M3T50_RS20080 (M3T50_20080) 4127609..4127752 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3T50_RS20085 (M3T50_20085) 4127857..4128825 - 969 WP_004151446.1 VirK/YbjX family protein -
M3T50_RS20090 (M3T50_20090) 4128982..4129635 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M3T50_RS20095 (M3T50_20095) 4129632..4129823 - 192 WP_002911395.1 YebW family protein -
M3T50_RS20100 (M3T50_20100) 4129921..4130160 - 240 WP_002911393.1 YebV family protein -
M3T50_RS20105 (M3T50_20105) 4130276..4131709 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245752 NZ_CP097654:4127132-4127234 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245752 NZ_CP097654:c4127241-4127096 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References