Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-couple_hipB
Location 2688226..2688860 Replicon chromosome
Accession NZ_CP097649
Organism Brevundimonas albigilva strain TT17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M8231_RS13325 Protein ID WP_250201690.1
Coordinates 2688226..2688471 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M8231_RS13330 Protein ID WP_249749554.1
Coordinates 2688468..2688860 (+) Length 131 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8231_RS13295 (M8231_13295) 2683737..2684246 - 510 WP_249749561.1 prepilin peptidase -
M8231_RS13300 (M8231_13300) 2684312..2684506 - 195 WP_249749560.1 hypothetical protein -
M8231_RS13305 (M8231_13305) 2684609..2685115 - 507 WP_249749559.1 hypothetical protein -
M8231_RS13310 (M8231_13310) 2685279..2686481 + 1203 WP_249749558.1 threonine ammonia-lyase -
M8231_RS13315 (M8231_13315) 2686462..2686986 + 525 WP_249749557.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
M8231_RS13320 (M8231_13320) 2687016..2688167 - 1152 WP_249749556.1 tRNA epoxyqueuosine(34) reductase QueG -
M8231_RS13325 (M8231_13325) 2688226..2688471 + 246 WP_250201690.1 hypothetical protein Toxin
M8231_RS13330 (M8231_13330) 2688468..2688860 + 393 WP_249749554.1 helix-turn-helix transcriptional regulator Antitoxin
M8231_RS13335 (M8231_13335) 2688917..2691616 + 2700 WP_249749553.1 [protein-PII] uridylyltransferase -
M8231_RS13340 (M8231_13340) 2691644..2693239 + 1596 WP_249749552.1 murein biosynthesis integral membrane protein MurJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(77-127)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8861.26 Da        Isoelectric Point: 11.6785

>T245725 WP_250201690.1 NZ_CP097649:2688226-2688471 [Brevundimonas albigilva]
VKTIVLTNSAARQFDALPASARATISAALDAYAMHGRGDVKALNGRLGFRLRVGRYRVIFTEDMTTILAIHIGPRQTGTY
R

Download         Length: 246 bp

Antitoxin


Download         Length: 131 a.a.        Molecular weight: 14087.77 Da        Isoelectric Point: 4.4859

>AT245725 WP_249749554.1 NZ_CP097649:2688468-2688860 [Brevundimonas albigilva]
MNRPLHAQHITTPAGEELVILPRAEYEALTAGLDQDEDEADIAAFDAAMADLEAGVDERLPVEVSTLILKGASRLTAWRK
HRGWTQQALAEAATIGQGYLSEIERGHKTGGPETLRRLAEVLDVPADHIG

Download         Length: 393 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References