Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 823402..824075 Replicon chromosome
Accession NZ_CP097649
Organism Brevundimonas albigilva strain TT17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M8231_RS04075 Protein ID WP_250202315.1
Coordinates 823402..823824 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M8231_RS04080 Protein ID WP_250202316.1
Coordinates 823863..824075 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8231_RS04040 (M8231_04040) 819227..819508 - 282 WP_250202309.1 helix-turn-helix domain-containing protein -
M8231_RS04045 (M8231_04045) 819644..820174 - 531 WP_250202310.1 DUF2285 domain-containing protein -
M8231_RS04050 (M8231_04050) 820533..820793 - 261 WP_250202311.1 DUF2285 domain-containing protein -
M8231_RS04055 (M8231_04055) 820890..821156 - 267 WP_250202312.1 helix-turn-helix transcriptional regulator -
M8231_RS04060 (M8231_04060) 821476..821802 - 327 WP_250202313.1 DUF736 domain-containing protein -
M8231_RS04065 (M8231_04065) 822376..822816 - 441 WP_250202314.1 hypothetical protein -
M8231_RS04070 (M8231_04070) 822949..823116 - 168 WP_169800607.1 hypothetical protein -
M8231_RS04075 (M8231_04075) 823402..823824 - 423 WP_250202315.1 type II toxin-antitoxin system VapC family toxin Toxin
M8231_RS04080 (M8231_04080) 823863..824075 - 213 WP_250202316.1 plasmid stabilization protein Antitoxin
M8231_RS04085 (M8231_04085) 824160..825086 - 927 WP_250202317.1 DUF2493 domain-containing protein -
M8231_RS04090 (M8231_04090) 825479..825649 + 171 WP_250202318.1 hypothetical protein -
M8231_RS04095 (M8231_04095) 825670..825981 + 312 WP_250202319.1 helix-turn-helix transcriptional regulator -
M8231_RS04100 (M8231_04100) 825974..827227 + 1254 WP_250202320.1 HipA domain-containing protein -
M8231_RS04105 (M8231_04105) 827249..828313 - 1065 WP_250202321.1 toprim domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15082.22 Da        Isoelectric Point: 4.4891

>T245722 WP_250202315.1 NZ_CP097649:c823824-823402 [Brevundimonas albigilva]
MILLNTNVVSEAMKPAPDEAVRTWLDEQAAETLFLSSVTIAELMFGIGALPDGRRKDRLTDALDGVMELFTDRILPFDID
AARHYADLAVKARAAGKGFPTPDGYIAAIAAAKGFVVATRDTSAFDAANVEVIDPWKTGR

Download         Length: 423 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7719.79 Da        Isoelectric Point: 11.0377

>AT245722 WP_250202316.1 NZ_CP097649:c824075-823863 [Brevundimonas albigilva]
MPAVTIRNLSDATHRALKVRAAQHGRSTEAEMRAILEAAVRPDTRLRLGTALAERSRRLGLTNEDIDALD

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References