Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/Phd(antitoxin)
Location 715057..715508 Replicon chromosome
Accession NZ_CP097636
Organism Aquincola tertiaricarbonis strain RN12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MW290_RS17505 Protein ID WP_250198985.1
Coordinates 715057..715233 (-) Length 59 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MW290_RS17510 Protein ID WP_250198986.1
Coordinates 715254..715508 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW290_RS17485 (MW290_17485) 711350..712048 + 699 WP_250200040.1 FadR/GntR family transcriptional regulator -
MW290_RS17490 (MW290_17490) 712108..713088 + 981 WP_250198982.1 tripartite tricarboxylate transporter substrate binding protein -
MW290_RS17495 (MW290_17495) 713106..713900 + 795 WP_250198983.1 aldolase/citrate lyase family protein -
MW290_RS17500 (MW290_17500) 713932..714828 + 897 WP_259373501.1 2-hydroxy-3-oxopropionate reductase -
MW290_RS17505 (MW290_17505) 715057..715233 - 177 WP_250198985.1 hypothetical protein Toxin
MW290_RS17510 (MW290_17510) 715254..715508 - 255 WP_250198986.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MW290_RS17515 (MW290_17515) 715626..716537 - 912 WP_250198987.1 DMT family transporter -
MW290_RS17520 (MW290_17520) 716628..717560 + 933 WP_250198988.1 LysR family transcriptional regulator -
MW290_RS17525 (MW290_17525) 717544..718425 - 882 WP_250198989.1 3',5'-nucleoside bisphosphate phosphatase -
MW290_RS17530 (MW290_17530) 718464..719525 - 1062 WP_250200042.1 PQQ-dependent sugar dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6539.69 Da        Isoelectric Point: 12.0385

>T245705 WP_250198985.1 NZ_CP097636:c715233-715057 [Aquincola tertiaricarbonis]
VLPQLRRKSPDPVRRLARPLPAVDRLLTATALHHGLILVTRNVRDVSDLGVQVLNPWE

Download         Length: 177 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9200.45 Da        Isoelectric Point: 4.7045

>AT245705 WP_250198986.1 NZ_CP097636:c715508-715254 [Aquincola tertiaricarbonis]
MQTWQMQDAKARLSEVVKRAEQDGPQDITVHGKSVAVVLSRAAFERMSGQQASLLAFMQASPLAGLDDELVIERDASLTR
DVSL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References