Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2021201..2021346 Replicon chromosome
Accession NZ_CP097626
Organism Klebsiella pneumoniae strain 140253

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2021237..2021339 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2021201..2021346 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9P58_RS09875 (M9P58_09875) 2016331..2018391 + 2061 WP_004151449.1 oligopeptidase B -
M9P58_RS09880 (M9P58_09880) 2018395..2019054 - 660 WP_002911407.1 exodeoxyribonuclease X -
M9P58_RS09885 (M9P58_09885) 2019133..2019363 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M9P58_RS09890 (M9P58_09890) 2019476..2019850 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M9P58_RS09895 (M9P58_09895) 2019854..2020723 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M9P58_RS09900 (M9P58_09900) 2020740..2021078 + 339 WP_002911404.1 YebY family protein -
- 2021201..2021346 - 146 - - Antitoxin
- 2021237..2021339 + 103 - - Toxin
M9P58_RS09905 (M9P58_09905) 2021714..2021857 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M9P58_RS09910 (M9P58_09910) 2021962..2022930 - 969 WP_004151446.1 VirK/YbjX family protein -
M9P58_RS09915 (M9P58_09915) 2023087..2023740 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M9P58_RS09920 (M9P58_09920) 2023737..2023928 - 192 WP_002911395.1 YebW family protein -
M9P58_RS09925 (M9P58_09925) 2024026..2024265 - 240 WP_002911393.1 YebV family protein -
M9P58_RS09930 (M9P58_09930) 2024381..2025814 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245678 NZ_CP097626:2021237-2021339 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245678 NZ_CP097626:c2021346-2021201 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References