Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 449427..450001 Replicon chromosome
Accession NZ_CP097606
Organism Pasteurella multocida strain 10957

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag M8846_RS02085 Protein ID WP_061406134.1
Coordinates 449427..449711 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag M8846_RS02090 Protein ID WP_061406133.1
Coordinates 449708..450001 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8846_RS02065 (M8846_02065) 445220..446809 - 1590 WP_250191770.1 AAA family ATPase -
M8846_RS02070 (M8846_02070) 447094..447585 - 492 WP_284150420.1 NERD domain-containing protein -
M8846_RS02075 (M8846_02075) 447813..448148 + 336 WP_223848039.1 DUF3418 domain-containing protein -
M8846_RS02085 (M8846_02085) 449427..449711 + 285 WP_061406134.1 hypothetical protein Toxin
M8846_RS02090 (M8846_02090) 449708..450001 + 294 WP_061406133.1 putative addiction module antidote protein Antitoxin
M8846_RS02095 (M8846_02095) 450403..451080 - 678 WP_005751574.1 3-keto-L-gulonate-6-phosphate decarboxylase UlaD -
M8846_RS02100 (M8846_02100) 451098..451565 - 468 WP_005726755.1 PTS sugar transporter subunit IIA -
M8846_RS02105 (M8846_02105) 451610..453400 - 1791 WP_005726754.1 PTS ascorbate-specific subunit IIBC -
M8846_RS02110 (M8846_02110) 453750..454841 + 1092 WP_250191772.1 L-ascorbate 6-phosphate lactonase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-87)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10667.40 Da        Isoelectric Point: 10.2297

>T245656 WP_061406134.1 NZ_CP097606:449427-449711 [Pasteurella multocida]
VGRLKEVKILSAKSAVLARINKAMNGNFGDHKSIGNGLYEMRIIKGSGYRVYYGQYREVTYLLICGGDKSTQKSDIVKAR
ELWKEIKQQEEVKV

Download         Length: 285 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10947.88 Da        Isoelectric Point: 8.9149

>AT245656 WP_061406133.1 NZ_CP097606:449708-450001 [Pasteurella multocida]
MSKKKIKLKLFDIAEHLDSEEMIAAYLSEVLETCDTNEFISALSDVVRAKGMTELAAKTGLRRESLYKTLSYGSKPRFDT
IMKIMHSLGIKLVPTHI

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References