Detailed information of TA system TA024563

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 672674..673217
• Replicon: chromosome
• Accession: NC_013851
• Organism: Allochromatium vinosum DSM 180

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ALVIN_RS16915
• Protein ID: WP_012969810.1
• Coordinates: 672674..672973 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: D3RP25
• Locus tag: ALVIN_RS02900
• Protein ID: WP_012969811.1
• Coordinates: 672963..673217 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ALVIN_RS02875	667740..668462	-	723	WP_012969805.1	bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	-
ALVIN_RS02880	668616..669035	+	420	WP_012969806.1	SCP2 sterol-binding domain-containing protein	-
ALVIN_RS02885	669150..670529	-	1380	WP_012969807.1	alginate export family protein	-
ALVIN_RS17755	670519..670689	-	171	WP_012969808.1	hypothetical protein	-
ALVIN_RS16455	670696..672531	-	1836	WP_012969809.1	sodium:solute symporter family protein	-
ALVIN_RS16915	672674..672973	-	300	WP_012969810.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ALVIN_RS02900	672963..673217	-	255	WP_012969811.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ALVIN_RS02905	673327..676401	-	3075	WP_012969812.1	efflux RND transporter permease subunit	-
ALVIN_RS02910	676398..677522	-	1125	WP_012969813.1	efflux RND transporter periplasmic adaptor subunit	-
ALVIN_RS02915	677538..677924	-	387	WP_012969814.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11716.49 Da
• Isoelectric Point: 10.6528

>T24563 WP_012969810.1 NC_013851:c672973-672674 [Allochromatium vinosum DSM 180]
MSYELQFHPDAWDEWNRLDKSVREQLKKKLLERLEEPHIPASRLSGRQNRYKIKLKTVGYRLVYEVLNDRLIVLVVAVGR
RDRNAVYTAAARRQTHVSG

Nucleotide

• Length: 300 bp

>T24563 NC_013851:c672973-672674 [Allochromatium vinosum DSM 180]
ATGAGCTATGAGCTACAGTTCCATCCGGATGCCTGGGATGAGTGGAACAGACTGGACAAGAGCGTCAGAGAACAGCTCAA
GAAGAAGCTCCTGGAACGTCTGGAAGAACCCCATATCCCCGCTTCCAGGCTCTCTGGACGCCAAAACCGTTACAAGATCA
AACTGAAGACGGTCGGCTACCGGCTCGTATACGAAGTGCTGAACGATCGGCTGATCGTTCTGGTCGTTGCCGTTGGCAGG
CGCGATCGAAACGCTGTCTACACGGCCGCCGCCAGACGACAGACGCACGTCTCCGGCTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9080.38 Da
• Isoelectric Point: 4.3855

>AT24563 WP_012969811.1 NC_013851:c673217-672963 [Allochromatium vinosum DSM 180]
MTHRILAETTASISELKRNPMGTVAAGAGLPVAVLNRNEPAFYCVPAQAYEALMDRLEDLELNDIADARLNDGKAPLKVS
LDEL

Nucleotide

• Length: 255 bp

>AT24563 NC_013851:c673217-672963 [Allochromatium vinosum DSM 180]
ATGACGCATCGAATCCTGGCCGAAACGACGGCGAGCATTTCAGAGCTGAAACGCAATCCGATGGGCACGGTCGCGGCCGG
AGCCGGTCTTCCGGTGGCCGTCCTCAACCGCAACGAGCCGGCCTTTTATTGCGTGCCGGCGCAAGCCTACGAGGCCCTGA
TGGATCGCCTCGAAGATCTTGAACTGAACGACATCGCCGATGCCCGCCTGAATGACGGAAAGGCGCCGCTCAAGGTCTCC
CTGGATGAGCTATGA

Structures

Antitoxin

• AlphaFold DB: D3RP25