Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3734055..3734668 Replicon chromosome
Accession NZ_CP097576
Organism Microcystis aeruginosa str. Chao 1910

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M8120_RS18845 Protein ID WP_190357894.1
Coordinates 3734282..3734668 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M8120_RS18840 Protein ID WP_190357893.1
Coordinates 3734055..3734282 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8120_RS18825 (M8120_18650) 3731584..3731829 + 246 WP_190358710.1 hypothetical protein -
M8120_RS18830 (M8120_18655) 3731819..3732520 - 702 WP_265795427.1 hypothetical protein -
M8120_RS18835 (M8120_18660) 3733534..3734013 + 480 WP_190357892.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase -
M8120_RS18840 (M8120_18665) 3734055..3734282 + 228 WP_190357893.1 DUF2281 domain-containing protein Antitoxin
M8120_RS18845 (M8120_18670) 3734282..3734668 + 387 WP_190357894.1 type II toxin-antitoxin system VapC family toxin Toxin
M8120_RS18850 (M8120_18675) 3734761..3736518 + 1758 WP_190357895.1 arginine--tRNA ligase -
M8120_RS18855 (M8120_18680) 3737259..3737651 + 393 WP_190358883.1 Mo-dependent nitrogenase C-terminal domain-containing protein -
M8120_RS18860 (M8120_18685) 3737682..3738440 + 759 WP_190358884.1 hypothetical protein -
M8120_RS18865 (M8120_18690) 3738446..3738697 + 252 WP_012266136.1 hypothetical protein -
M8120_RS18870 (M8120_18695) 3738740..3739147 - 408 WP_190358885.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-127)

Antitoxin

Domain of unknown function DUF2281

(6-74)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14825.11 Da        Isoelectric Point: 4.8942

>T245629 WP_190357894.1 NZ_CP097576:3734282-3734668 [Microcystis aeruginosa str. Chao 1910]
MTSFLLDTHTFIWLTENDPNLPDNLREEIDFAPEVYVSIVSLWEIAIKLNLGKLALQKSYETIETKLEASDITLLSISFS
DTLKICTLPLHHRDPFDRMLIAQSINRTLILISKDTKFDAYNVPRKWT

Download         Length: 387 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8813.12 Da        Isoelectric Point: 4.1064

>AT245629 WP_190357893.1 NZ_CP097576:3734055-3734282 [Microcystis aeruginosa str. Chao 1910]
MNIDTKILETVEAMPELLKIELLHYAEYLMANYQSDVIIEKPSLRKRRSGILQGTFILPLSDDFDESLEDFQEYM

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References