Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 2674463..2674970 Replicon chromosome
Accession NZ_CP097576
Organism Microcystis aeruginosa str. Chao 1910

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag M8120_RS13440 Protein ID WP_043997958.1
Coordinates 2674701..2674970 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag M8120_RS13435 Protein ID WP_190358662.1
Coordinates 2674463..2674711 (-) Length 83 a.a.

Genomic Context

M8120_RS13415M8120_RS13445M8120_RS13450M8120_RS13460M8120_RS13410M8120_RS13420M8120_RS13425M8120_RS13430M8120_RS13435M8120_RS13440M8120_RS13455
Location: 2670976..2671932 (957 bp)
Type: Others
Protein ID: WP_190358660.1
Location: 2675178..2675504 (327 bp)
Type: Others
Protein ID: WP_190358663.1
Location: 2675508..2675849 (342 bp)
Type: Others
Protein ID: WP_002757208.1
Location: 2676858..2677947 (1090 bp)
Type: Others
Protein ID: Protein_2665
Location: 2669572..2670213 (642 bp)
Type: Others
Protein ID: WP_151696328.1
Location: 2672026..2672913 (888 bp)
Type: Others
Protein ID: WP_190358661.1
Location: 2672996..2673322 (327 bp)
Type: Others
Protein ID: WP_002748322.1
Location: 2673342..2673644 (303 bp)
Type: Others
Protein ID: WP_002738360.1
Location: 2674463..2674711 (249 bp)
Type: Antitoxin
Protein ID: WP_190358662.1
Location: 2674701..2674970 (270 bp)
Type: Toxin
Protein ID: WP_043997958.1
Location: 2676363..2676770 (408 bp)
Type: Others
Protein ID: Protein_2664
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M8120_RS13410 (M8120_13280)2669572..2670213-642WP_151696328.1LON peptidase substrate-binding domain-containing protein-
M8120_RS13415 (M8120_13285)2670976..2671932+957WP_190358660.1RNA polymerase sigma factor, RpoD/SigA family-
M8120_RS13420 (M8120_13290)2672026..2672913-888WP_190358661.1S-methyl-5'-thioadenosine phosphorylase-
M8120_RS13425 (M8120_13295)2672996..2673322-327WP_002748322.1urease subunit beta-
M8120_RS13430 (M8120_13300)2673342..2673644-303WP_002738360.1urease subunit gamma-
M8120_RS13435 (M8120_13305)2674463..2674711-249WP_190358662.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
M8120_RS13440 (M8120_13310)2674701..2674970-270WP_043997958.1type II toxin-antitoxin system HicA family toxinToxin
M8120_RS13445 (M8120_13315)2675178..2675504+327WP_190358663.1DUF433 domain-containing protein-
M8120_RS13450 (M8120_13320)2675508..2675849+342WP_002757208.1DUF5615 family PIN-like protein-
M8120_RS13455 (M8120_13325)2676363..2676770-408Protein_2664formylglycine-generating enzyme family protein-
M8120_RS13460 (M8120_13330)2676858..2677947+1090Protein_2665ISAs1 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(25-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10150.69 Da        Isoelectric Point: 10.0825

>T245625 WP_043997958.1 NZ_CP097576:c2674970-2674701 [Microcystis aeruginosa str. Chao 1910]
MALSKKQRKILDQIFEQPVRSDVVWTDIESLLEALGAEISEGRRLRVWVALKGVKAVFHRPHPRRETDKGAVVSVRRFLS
EAGVENDEV

Download         Length: 270 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9250.25 Da        Isoelectric Point: 4.2207

>AT245625 WP_190358662.1 NZ_CP097576:c2674711-2674463 [Microcystis aeruginosa str. Chao 1910]
MKYKGYEAVVSFDDEAGIFYGEVANVRDVITFQGESVAELQQAFADSVEDYLAFCAERGEKPEKPFSDSFLSQPHPKLHQ
QI

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References