Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 843221..843861 Replicon chromosome
Accession NZ_CP097576
Organism Microcystis aeruginosa str. Chao 1910

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M8120_RS04100 Protein ID WP_190356878.1
Coordinates 843463..843861 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M8120_RS04095 Protein ID WP_190356877.1
Coordinates 843221..843466 (+) Length 82 a.a.

Genomic Context


M8120_RS04080M8120_RS04095M8120_RS04100M8120_RS04115M8120_RS04120M8120_RS04130M8120_RS04060M8120_RS04065M8120_RS04070M8120_RS04075M8120_RS04085M8120_RS04090M8120_RS04105M8120_RS04110
Location: 841956..842252 (297 bp)
Type: Others
Protein ID: Protein_810
Location: 843221..843466 (246 bp)
Type: Antitoxin
Protein ID: WP_190356877.1
Location: 843463..843861 (399 bp)
Type: Toxin
Protein ID: WP_190356878.1
Location: 845678..846175 (498 bp)
Type: Others
Protein ID: WP_190356880.1
Location: 846640..847539 (900 bp)
Type: Others
Protein ID: WP_190356881.1
Location: 847964..848627 (664 bp)
Type: Others
Protein ID: Protein_819
Location: 839028..840251 (1224 bp)
Type: Others
Protein ID: Protein_806
Location: 840441..840728 (288 bp)
Type: Others
Protein ID: WP_242029995.1
Location: 840976..841215 (240 bp)
Type: Others
Protein ID: WP_242029996.1
Location: 841374..841529 (156 bp)
Type: Others
Protein ID: WP_190356886.1
Location: 842291..842617 (327 bp)
Type: Others
Protein ID: WP_002757286.1
Location: 842601..842864 (264 bp)
Type: Others
Protein ID: WP_002757287.1
Location: 844165..844428 (264 bp)
Type: Others
Protein ID: WP_190356879.1
Location: 844597..845457 (861 bp)
Type: Others
Protein ID: WP_242029997.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M8120_RS04060 (M8120_04025)839028..840251-1224Protein_806transposase-
M8120_RS04065 (M8120_04030)840441..840728-288WP_242029995.1hypothetical protein-
M8120_RS04070 (M8120_04035)840976..841215-240WP_242029996.1hypothetical protein-
M8120_RS04075 (M8120_04040)841374..841529-156WP_190356886.1hypothetical protein-
M8120_RS04080 (M8120_04045)841956..842252+297Protein_810arginase family protein-
M8120_RS04085 (M8120_04050)842291..842617-327WP_002757286.1DUF5615 family PIN-like protein-
M8120_RS04090 (M8120_04055)842601..842864-264WP_002757287.1DUF433 domain-containing protein-
M8120_RS04095 (M8120_04060)843221..843466+246WP_190356877.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
M8120_RS04100 (M8120_04065)843463..843861+399WP_190356878.1type II toxin-antitoxin system VapC family toxinToxin
M8120_RS04105 (M8120_04070)844165..844428-264WP_190356879.1DUF2442 domain-containing protein-
M8120_RS04110 (M8120_04075)844597..845457-861WP_242029997.1PEP-CTERM sorting domain-containing protein-
M8120_RS04115 (M8120_04080)845678..846175+498WP_190356880.1ATPase-
M8120_RS04120 (M8120_04085)846640..847539+900WP_190356881.1agmatinase-
M8120_RS04130 (M8120_04095)847964..848627+664Protein_819IS1 family transposase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--840976..85496913993


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 133 a.a.        Molecular weight: 14991.04 Da        Isoelectric Point: 4.4046

>T245617 WP_190356878.1 NZ_CP097576:843463-843861 [Microcystis aeruginosa str. Chao 1910]
VRILLDTQCWLWWFVQPDKLSENVIEQIANESNEVWFSVASVWEMGIKVSIGKLSLPEQIDDYVSTRMTQLGARSLEINA
SHALRAAALPLHHRDPFDRMLIAQAQVEDMTLVSADSTFNQYEVSLLWAASS

Download         Length: 399 bp


Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8881.10 Da        Isoelectric Point: 4.7361

>AT245617 WP_190356877.1 NZ_CP097576:843221-843466 [Microcystis aeruginosa str. Chao 1910]
METVNIHQAKTSLSRLLSRVELGEEIVISNRGIPIAKLVPFRTSLDRRSSLGQDRGMFTVPDDFNAPLPEDILGAFEGGA
E

Download         Length: 246 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References