Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 1427391..1428649 | Replicon | chromosome |
Accession | NZ_CP097575 | ||
Organism | Pseudomonas aeruginosa strain UNC_PaerCF25 |
Toxin (Protein)
Gene name | - | Uniprot ID | Q9I4U4 |
Locus tag | M9A05_RS06555 | Protein ID | WP_003112528.1 |
Coordinates | 1427391..1428146 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | M9A05_RS06560 | Protein ID | WP_003086329.1 |
Coordinates | 1428281..1428649 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M9A05_RS06545 (M9A05_06545) | 1422564..1425107 | + | 2544 | WP_250177674.1 | acyl-homoserine-lactone acylase QuiP | - |
M9A05_RS06550 (M9A05_06550) | 1425262..1426623 | - | 1362 | WP_003134034.1 | DNA recombination protein RmuC | - |
M9A05_RS06555 (M9A05_06555) | 1427391..1428146 | - | 756 | WP_003112528.1 | RES family NAD+ phosphorylase | Toxin |
M9A05_RS06560 (M9A05_06560) | 1428281..1428649 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
M9A05_RS06565 (M9A05_06565) | 1428722..1430008 | - | 1287 | WP_003163134.1 | FAD-binding oxidoreductase | - |
M9A05_RS06570 (M9A05_06570) | 1430064..1431557 | - | 1494 | WP_003086325.1 | aldehyde dehydrogenase family protein | - |
M9A05_RS06575 (M9A05_06575) | 1431732..1432208 | + | 477 | WP_003112531.1 | hypothetical protein | - |
M9A05_RS06580 (M9A05_06580) | 1432211..1432486 | - | 276 | WP_010792073.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28278.42 Da Isoelectric Point: 7.7294
>T245612 WP_003112528.1 NZ_CP097575:c1428146-1427391 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT245612 WP_003086329.1 NZ_CP097575:c1428649-1428281 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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