Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3964181..3964838 Replicon chromosome
Accession NZ_CP097572
Organism Enterobacter kobei strain C210239

Toxin (Protein)


Gene name cptA Uniprot ID A0A2W0G6Z0
Locus tag M8978_RS18870 Protein ID WP_014885136.1
Coordinates 3964181..3964591 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag M8978_RS18875 Protein ID WP_010435322.1
Coordinates 3964572..3964838 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8978_RS18850 (M8978_18850) 3960175..3961908 - 1734 WP_023331239.1 single-stranded-DNA-specific exonuclease RecJ -
M8978_RS18855 (M8978_18855) 3961914..3962627 - 714 WP_045134112.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
M8978_RS18860 (M8978_18860) 3962656..3963552 - 897 WP_014885134.1 site-specific tyrosine recombinase XerD -
M8978_RS18865 (M8978_18865) 3963654..3964175 + 522 WP_014885135.1 flavodoxin FldB -
M8978_RS18870 (M8978_18870) 3964181..3964591 - 411 WP_014885136.1 protein YgfX Toxin
M8978_RS18875 (M8978_18875) 3964572..3964838 - 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
M8978_RS18880 (M8978_18880) 3965133..3966113 + 981 WP_045134111.1 tRNA-modifying protein YgfZ -
M8978_RS18885 (M8978_18885) 3966198..3966857 - 660 WP_023331242.1 hemolysin III family protein -
M8978_RS18890 (M8978_18890) 3967123..3967854 + 732 WP_014885139.1 MurR/RpiR family transcriptional regulator -
M8978_RS18895 (M8978_18895) 3967971..3969404 + 1434 WP_014885140.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16135.04 Da        Isoelectric Point: 10.7510

>T245610 WP_014885136.1 NZ_CP097572:c3964591-3964181 [Enterobacter kobei]
VVLWQSDLRVSWRSQWMSLMLHGLVAAIVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNSGMMLRLRNVDGGRCQHLWLAADSMDASEWRDLRRMLLQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT245610 WP_010435322.1 NZ_CP097572:c3964838-3964572 [Enterobacter kobei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2W0G6Z0

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References