Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 32331..32881 Replicon plasmid pPAC1.3a
Accession NZ_CP097558
Organism Pseudomonas aeruginosa strain C1.3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAC13_RS34075 Protein ID WP_034061810.1
Coordinates 32603..32881 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAC13_RS34070 Protein ID WP_034061812.1
Coordinates 32331..32603 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAC13_RS34040 (PAC13_33970) 27642..28307 + 666 WP_034061819.1 hypothetical protein -
PAC13_RS34045 (PAC13_33975) 28445..28711 + 267 WP_034061816.1 helix-turn-helix transcriptional regulator -
PAC13_RS34050 (PAC13_33980) 28677..29489 + 813 Protein_41 site-specific integrase -
PAC13_RS34055 (PAC13_33985) 29651..30799 + 1149 WP_034061814.1 site-specific integrase -
PAC13_RS34060 (PAC13_33990) 30941..31687 + 747 WP_034061813.1 DUF2807 domain-containing protein -
PAC13_RS34065 (PAC13_33995) 31697..32137 + 441 WP_128734628.1 hypothetical protein -
PAC13_RS34070 (PAC13_34000) 32331..32603 + 273 WP_034061812.1 ribbon-helix-helix domain-containing protein Antitoxin
PAC13_RS34075 (PAC13_34005) 32603..32881 + 279 WP_034061810.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAC13_RS34080 (PAC13_34010) 32883..33710 + 828 WP_034061809.1 hypothetical protein -
PAC13_RS34085 (PAC13_34015) 33724..33966 + 243 WP_034061808.1 hypothetical protein -
PAC13_RS34090 (PAC13_34020) 33979..34491 - 513 WP_044305333.1 hypothetical protein -
PAC13_RS34095 (PAC13_34025) 34488..36338 - 1851 WP_049267175.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..177192 177192


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10844.46 Da        Isoelectric Point: 8.5041

>T245581 WP_034061810.1 NZ_CP097558:32603-32881 [Pseudomonas aeruginosa]
MELKWTSKALSDLARLYEFLAAVNRPAAARTVQQLTVTPTTLLTNPRIGERLEEFEPRDVRRILVGHYEMRYEIAADSTI
YLLRLWHTREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10054.25 Da        Isoelectric Point: 4.8616

>AT245581 WP_034061812.1 NZ_CP097558:32331-32603 [Pseudomonas aeruginosa]
MAATAKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWLDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPH

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References