Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 5064768..5066026 | Replicon | chromosome |
Accession | NZ_CP097557 | ||
Organism | Pseudomonas aeruginosa strain C1.3 |
Toxin (Protein)
Gene name | - | Uniprot ID | V6AJ34 |
Locus tag | PAC13_RS24375 | Protein ID | WP_003086331.1 |
Coordinates | 5064768..5065523 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PAC13_RS24380 | Protein ID | WP_003086329.1 |
Coordinates | 5065658..5066026 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PAC13_RS24365 (PAC13_24315) | 5059939..5062482 | + | 2544 | WP_009315399.1 | acyl-homoserine-lactone acylase QuiP | - |
PAC13_RS24370 (PAC13_24320) | 5062637..5063998 | - | 1362 | WP_003134034.1 | DNA recombination protein RmuC | - |
PAC13_RS24375 (PAC13_24325) | 5064768..5065523 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
PAC13_RS24380 (PAC13_24330) | 5065658..5066026 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PAC13_RS24385 (PAC13_24335) | 5066099..5067385 | - | 1287 | WP_003086327.1 | FAD-binding oxidoreductase | - |
PAC13_RS24390 (PAC13_24340) | 5067441..5069030 | - | 1590 | WP_003123191.1 | aldehyde dehydrogenase family protein | - |
PAC13_RS24395 (PAC13_24345) | 5069109..5069585 | + | 477 | WP_003112531.1 | hypothetical protein | - |
PAC13_RS24400 (PAC13_24350) | 5069588..5069863 | - | 276 | WP_023088486.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T245579 WP_003086331.1 NZ_CP097557:c5065523-5064768 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT245579 WP_003086329.1 NZ_CP097557:c5066026-5065658 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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