Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-ArgA |
Location | 4844767..4845586 | Replicon | chromosome |
Accession | NZ_CP097554 | ||
Organism | Klebsiella michiganensis strain YZUMF202001 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | J5WT09 |
Locus tag | M8333_RS22890 | Protein ID | WP_004110819.1 |
Coordinates | 4845329..4845586 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | - |
Locus tag | M8333_RS22885 | Protein ID | WP_128696737.1 |
Coordinates | 4844767..4845318 (-) | Length | 184 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M8333_RS22865 (M8333_22865) | 4840987..4841895 | - | 909 | WP_128696738.1 | transcriptional regulator GcvA | - |
M8333_RS22870 (M8333_22870) | 4842015..4842902 | + | 888 | WP_064405204.1 | DMT family transporter | - |
M8333_RS22875 (M8333_22875) | 4843121..4843867 | - | 747 | WP_224227290.1 | class I SAM-dependent methyltransferase | - |
M8333_RS22880 (M8333_22880) | 4844291..4844653 | - | 363 | Protein_4502 | class I SAM-dependent methyltransferase | - |
M8333_RS22885 (M8333_22885) | 4844767..4845318 | - | 552 | WP_128696737.1 | N-acetyltransferase | Antitoxin |
M8333_RS22890 (M8333_22890) | 4845329..4845586 | - | 258 | WP_004110819.1 | YjhX family toxin | Toxin |
M8333_RS22895 (M8333_22895) | 4846262..4847446 | + | 1185 | WP_014228054.1 | mannonate dehydratase | - |
M8333_RS22900 (M8333_22900) | 4847520..4848995 | + | 1476 | WP_128696736.1 | fructuronate reductase | - |
M8333_RS22905 (M8333_22905) | 4849134..4849910 | + | 777 | WP_004847986.1 | Uxu operon transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9552.07 Da Isoelectric Point: 11.1381
>T245562 WP_004110819.1 NZ_CP097554:c4845586-4845329 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 184 a.a. Molecular weight: 20064.84 Da Isoelectric Point: 6.3270
>AT245562 WP_128696737.1 NZ_CP097554:c4845318-4844767 [Klebsiella michiganensis]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGELIRHGIEQLKAMGSQTVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGELIRHGIEQLKAMGSQTVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE
Download Length: 552 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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