Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 3823631..3824211 Replicon chromosome
Accession NZ_CP097480
Organism Chroococcidiopsis sp. CCNUC1

Toxin (Protein)


Gene name mazF Uniprot ID K9U3S3
Locus tag M5J74_RS17845 Protein ID WP_015155424.1
Coordinates 3823631..3823891 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag M5J74_RS17850 Protein ID WP_181246392.1
Coordinates 3823885..3824211 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5J74_RS17815 (M5J74_17815) 3818775..3819518 + 744 WP_106167415.1 phycobilisome rod-core linker polypeptide -
M5J74_RS17820 (M5J74_17820) 3819739..3820500 + 762 WP_015155419.1 phycobilisome rod-core linker polypeptide -
M5J74_RS17825 (M5J74_17825) 3820728..3821201 + 474 WP_106168164.1 hypothetical protein -
M5J74_RS17830 (M5J74_17830) 3821315..3822187 - 873 WP_250012641.1 NAD(P)-dependent oxidoreductase -
M5J74_RS17835 (M5J74_17835) 3822479..3822886 + 408 WP_106168163.1 50S ribosomal protein L21 -
M5J74_RS17840 (M5J74_17840) 3822983..3823270 + 288 WP_015155423.1 50S ribosomal protein L27 -
M5J74_RS17845 (M5J74_17845) 3823631..3823891 + 261 WP_015155424.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
M5J74_RS17850 (M5J74_17850) 3823885..3824211 + 327 WP_181246392.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
M5J74_RS17855 (M5J74_17855) 3824214..3825188 + 975 WP_250012642.1 XdhC family protein -
M5J74_RS17860 (M5J74_17860) 3825233..3826195 - 963 WP_250012643.1 DUF6263 family protein -
M5J74_RS17865 (M5J74_17865) 3826404..3826970 + 567 WP_250012644.1 hypothetical protein -
M5J74_RS17870 (M5J74_17870) 3826981..3827517 - 537 WP_250012645.1 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR -
M5J74_RS17875 (M5J74_17875) 3827518..3827748 + 231 WP_250012646.1 hypothetical protein -
M5J74_RS17880 (M5J74_17880) 3827790..3829076 - 1287 WP_015155430.1 aminopeptidase P N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

SpoVT-AbrB domain

(10-45)

Antitoxin

mRNA interferase PemK-like

(1-105)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9841.17 Da        Isoelectric Point: 4.4992

>T245500 WP_015155424.1 NZ_CP097480:3823631-3823891 [Chroococcidiopsis sp. CCNUC1]
MGTGIRTRIVRIGNSQGIRIPKPLLEQSGIDTEVEIEVQDECLIVRAASRSRIGWDKAFAAMAEQKDDVLLDDVNITEWD
RTEWKW

Download         Length: 261 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12136.24 Da        Isoelectric Point: 9.1583

>AT245500 WP_181246392.1 NZ_CP097480:3823885-3824211 [Chroococcidiopsis sp. CCNUC1]
MVVKRFDVFLINLHPPTVGSEIQKTRPCVIVSPNEMNHYIATVIVAPMTTKGQPYPTRIACQFQGKDGQIVLDQIRTVDK
TRLVKKLGQINSNEQKAVLDILAEMFAE

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K9U3S3

Antitoxin

Source ID Structure

References