Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 559028..559683 Replicon chromosome
Accession NZ_CP097463
Organism Jatrophihabitans sp. SB3-54

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M6B22_RS02705 Protein ID WP_269444238.1
Coordinates 559246..559683 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M6B22_RS02700 Protein ID WP_269444237.1
Coordinates 559028..559249 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M6B22_RS02680 (M6B22_02690) 555003..555605 - 603 WP_269444233.1 class I SAM-dependent methyltransferase -
M6B22_RS02685 (M6B22_02695) 555697..556596 + 900 WP_269444234.1 ABC transporter ATP-binding protein -
M6B22_RS02690 (M6B22_02700) 556593..558236 + 1644 WP_269444235.1 hypothetical protein -
M6B22_RS02695 (M6B22_02710) 558508..558849 + 342 WP_269444236.1 type II toxin-antitoxin system PemK/MazF family toxin -
M6B22_RS02700 (M6B22_02715) 559028..559249 + 222 WP_269444237.1 antitoxin Antitoxin
M6B22_RS02705 (M6B22_02720) 559246..559683 + 438 WP_269444238.1 PIN domain nuclease Toxin
M6B22_RS02715 (M6B22_02730) 559935..560303 - 369 WP_269444239.1 TIGR02611 family protein -
M6B22_RS02720 (M6B22_02735) 560446..561507 + 1062 WP_269444240.1 CoA ester lyase -
M6B22_RS02725 (M6B22_02740) 561500..562357 + 858 WP_269444241.1 CoA ester lyase -
M6B22_RS02730 (M6B22_02745) 562364..563353 - 990 WP_269444242.1 XdhC/CoxI family protein -
M6B22_RS02735 (M6B22_02750) 563387..563668 - 282 WP_269444243.1 metal-sensitive transcriptional regulator -
M6B22_RS02740 (M6B22_02755) 563744..563950 + 207 WP_269444244.1 copper ion binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(10-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15852.26 Da        Isoelectric Point: 6.8843

>T245492 WP_269444238.1 NZ_CP097463:559246-559683 [Jatrophihabitans sp. SB3-54]
VTAAETRRWLIDKSALVRLSESLDASEWISRIDRGLVRIATVTILEVGFSARSADDLRAKLRRPPVAAMPIENATPRIET
RAIEVQESLAGLGHHRAPSVPDLIIAAIAELAGLVVLHVDKDFELIAGVTQQPTERLRLAQPHST

Download         Length: 438 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8413.48 Da        Isoelectric Point: 4.3558

>AT245492 WP_269444237.1 NZ_CP097463:559028-559249 [Jatrophihabitans sp. SB3-54]
MSDVLIRDVPDDVLAAVESHATKLGLSRNEYLRRQLAQDAMRSTVPVTMDDLRWFTQTFSDLAESEVMRQAWE

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References